DiseaseID 3554
梅克尔细胞癌
disease
NCI2016_NCI-GLOSS_1602D:A rare type of cancer that forms on or just beneath the skin, usually in parts of the body that have been exposed to the sun. It is most common in older people and in people with weakened immune s
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Disease: 1Symptom: 1Target: 20Links: 25
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 3554
- Core Entity Id
- 59774
- Source Entity Count
- 1
- Preferred Name
- Merkel Cell Carcinoma
- Name Cn
- 梅克尔细胞癌
- Name Pinyin
- Mei Ke Er Xi Bao Ai
- Name En
- Merkel Cell Carcinoma
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Neoplastic Process
- Disgenet Type
- disease
- Mesh Class
- Infections; Neoplasms
- Do Class
- Hpo Class
- Neoplasm; Abnormality of the integument; Abnormality of the endocrine system
- Mesh Class Name
- Neoplasms; Infections
- Hpo Class Name
- Abnormality of the integument; Abnormality of the endocrine system; Neoplasm
- Do Class Name
- Disease Definition
- NCI2016_NCI-GLOSS_1602D:A rare type of cancer that forms on or just beneath the skin, usually in parts of the body that have been exposed to the sun. It is most common in older people and in people with weakened immune systems.|NCI2016_02D:A rare malignant cutaneous tumor seen in elderly patients. Its usual location is on the head, neck and extremities. The tumor is composed of small round cells with scanty cytoplasm arranged in a trabecular pattern, or in ill-defined nodules or in a diffuse pattern. The tumor cells contain cytoplasmic membrane-bound dense core granules resembling neurosecretory granules.|MSH2017_2016_08_12:A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)|HPO2016_07_04:A malignant cutaneous tumor of the elderly that is characterized by an aggressive course with regional nodal involvement, distant metastases and a high rate of recurrence. Most patients present with rapidly growing, painless, firm, non-tender, dome-shaped red, occasionally ulcerated skin nodules, which have a red or bluish color, measuring up to several centimeters, on predominantly sun-exposed areas of the body. The overlying skin is smooth and shiny, sometimes exhibiting ulcerative, acneiform or telangiectatic features. [HPO:probinson, pmid:16565213]
- Version
- v2
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Merkel Cell Carcinoma
Role
preferred
Name
Anaplastic Carcinoma of The Skin
Role
alias
Name
Carcinoma, Merkel Cell
Role
alias
Name
Cutaneous Apudoma
Role
alias
Name
Merkel Cell Cancer of The Skin
Role
alias
Name
Merkel Cell Skin Cancer
Role
alias
Name
Neuroendocrine Carcinoma of The Skin
Role
alias
Name
Neuroendocrine Tumor of The Skin
Role
alias
Name
Primary Small Cell Carcinoma of The Skin
Role
alias
Name
Primary Undifferentiated Carcinoma of The Skin
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0030447
Herb
HBDIS000456
Me Sh
D015266
Umls
C0007129
Icd10
C4AC4A.9
Sym Map
SMDE10913
Dis Ge Net
C0007129
Umls Sty
T191
Hpo Class
HP:0000818HP:0001574HP:0002664
Me Sh Class
C01C04
Etcm Disease
Merkel Cell Carcinoma
Tcmbank Disease
32341
Itcmdb Generated
ITX-DISEASE-EDB415BFA9DA
Attributes
Merged source attributes and domain-specific metadata.
Version
v2
Suppress
0
Page Title
Disease Merkel Cell Carcinoma Details page
Disease Type
disease
Hpo Class Name
Abnormality of the integument; Abnormality of the endocrine system; Neoplasm
Hpo Disease Class
Neoplasm; Abnormality of the integument; Abnormality of the endocrine system
Umls Disease Type
Neoplastic Process
Basic Information
Disease Name
Merkel Cell Carcinoma
Global Category
Cancer diseases;Rare diseases
Anatomical Category
Endocrine diseases;Immune diseases;Neuronal diseases;Skin diseases
Disease Definition
NCI2016_NCI-GLOSS_1602D:A rare type of cancer that forms on or just beneath the skin, usually in parts of the body that have been exposed to the sun. It is most common in older people and in people with weakened immune systems.|NCI2016_02D:A rare malignant cutaneous tumor seen in elderly patients. Its usual location is on the head, neck and extremities. The tumor is composed of small round cells with scanty cytoplasm arranged in a trabecular pattern, or in ill-defined nodules or in a diffuse pattern. The tumor cells contain cytoplasmic membrane-bound dense core granules resembling neurosecretory granules.|MSH2017_2016_08_12:A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)|HPO2016_07_04:A malignant cutaneous tumor of the elderly that is characterized by an aggressive course with regional nodal involvement, distant metastases and a high rate of recurrence. Most patients present with rapidly growing, painless, firm, non-tender, dome-shaped red, occasionally ulcerated skin nodules, which have a red or bluish color, measuring up to several centimeters, on predominantly sun-exposed areas of the body. The overlying skin is smooth and shiny, sometimes exhibiting ulcerative, acneiform or telangiectatic features. [HPO:probinson, pmid:16565213]
Me Sh Disease Class
Infections; Neoplasms
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Neoplasms; Infections
Umls Semantic Type Name
Neoplastic Process