DiseaseID 3493
增殖性红斑
disease
NCI2016_NCI-GLOSS_1602D:A skin disease marked by scaly or thickened patches on the skin and often caused by prolonged exposure to arsenic. The patches often occur on sun-exposed areas of the skin and in older white men.
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Disease: 1Symptom: 2Target: 11Links: 13
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 3493
- Core Entity Id
- 59704
- Source Entity Count
- 1
- Preferred Name
- Erythroplasia
- Name Cn
- 增殖性红斑
- Name Pinyin
- Zeng Zhi Xing Hong Ban
- Name En
- Erythroplasia
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Disease or Syndrome
- Disgenet Type
- disease
- Mesh Class
- NeoplasmsSkin and Connective Tissue Diseases; Male Urogenital Diseases; Neoplasms
- Do Class
- disease of anatomical entity; disease of cellular proliferation
- Hpo Class
- Mesh Class Name
- NeoplasmsNeoplasms; Skin and Connective Tissue Diseases; Male Urogenital Diseases
- Hpo Class Name
- Do Class Name
- disease of anatomical entity; disease of cellular proliferation
- Disease Definition
- NCI2016_NCI-GLOSS_1602D:A skin disease marked by scaly or thickened patches on the skin and often caused by prolonged exposure to arsenic. The patches often occur on sun-exposed areas of the skin and in older white men. These patches may become malignant (cancer).|NCI2016_02D:A form of squamous cell carcinoma in situ. It is a distinct clinicopathological entity and arises from the skin or the mucocutaneous junction. It affects predominantly white males in their 6-8th decades of life. Exposed and non-exposed skin sites are equally affected. UV damage and ingestion of inorganic arsenic may play a role in the development of the disease. On the skin surface, it presents as a single or multiple erythematous, scaly, keratotic patches or plaques. The clinical entity of erythroplasia of Queyrat is regarded as Bowen disease of the penis and it presents as an asymptomatic, red, circumscribed plaque. Morphologically, Bowen disease is characterized by the presence of hyperkeratosis, parakeratosis, dyskeratosis, and acanthosis. The keratotic squamous cells are atypical and display hyperchromatism and abnormal mitotic figures. The dermoepidermal basement membrane is intact. Complete surgical removal of the lesion may be curative.|MSH2017_2016_08_12:A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective. (From Rook et al., Textbook of Dermatology, 4th ed, pp2428-9)
- Version
- v2
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Erythroplasia
Role
preferred
Name
Bowen'S Disease
Role
preferred
Name
Carcinoma In Situ of Penis
Role
preferred
Name
Penis
Role
alias
Name
Penis Carcinoma In Situ
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Herb
HBDIS000381HBDIS000983HBDIS003844
Me Sh
D001913D004919
Umls
C0006079
Icd10
D07.4
Sym Map
SMDE06551
Do Class
DOID:14566DOID:7
Dis Ge Net
C0006079C0014818C0154089
Umls Sty
T047T191
Me Sh Class
C04C12C17
Tcmbank Disease
20451233472465
Attributes
Merged source attributes and domain-specific metadata.
Version
v2
Suppress
0
Do Class Name
disease of anatomical entity; disease of cellular proliferation
Disease Type
disease
Do Disease Class
disease of anatomical entity; disease of cellular proliferation
Umls Disease Type
Disease or SyndromeNeoplastic Process
Disease Definition
NCI2016_NCI-GLOSS_1602D:A skin disease marked by scaly or thickened patches on the skin and often caused by prolonged exposure to arsenic. The patches often occur on sun-exposed areas of the skin and in older white men. These patches may become malignant (cancer).|NCI2016_02D:A form of squamous cell carcinoma in situ. It is a distinct clinicopathological entity and arises from the skin or the mucocutaneous junction. It affects predominantly white males in their 6-8th decades of life. Exposed and non-exposed skin sites are equally affected. UV damage and ingestion of inorganic arsenic may play a role in the development of the disease. On the skin surface, it presents as a single or multiple erythematous, scaly, keratotic patches or plaques. The clinical entity of erythroplasia of Queyrat is regarded as Bowen disease of the penis and it presents as an asymptomatic, red, circumscribed plaque. Morphologically, Bowen disease is characterized by the presence of hyperkeratosis, parakeratosis, dyskeratosis, and acanthosis. The keratotic squamous cells are atypical and display hyperchromatism and abnormal mitotic figures. The dermoepidermal basement membrane is intact. Complete surgical removal of the lesion may be curative.|MSH2017_2016_08_12:A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective. (From Rook et al., Textbook of Dermatology, 4th ed, pp2428-9)
Me Sh Disease Class
NeoplasmsSkin and Connective Tissue Diseases; Male Urogenital Diseases; Neoplasms
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
NeoplasmsNeoplasms; Skin and Connective Tissue Diseases; Male Urogenital Diseases
Umls Semantic Type Name
Disease or SyndromeNeoplastic Process