DiseaseID 3441

胆管癌

disease

Cholangiocarcinoma (CCA) is a biliary tract cancer (BTC, see this term) originating in the epithelium of the biliary tree, either intra or extra hepatic.

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Disease: 1Symptom: 12Target: 24Links: 36

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Record Fields

Scalar fields from the final disease record.

Disease Id: 3441
Core Entity Id: 59647
Source Entity Count: 1
Preferred Name: Cholangiocarcinoma
Name Cn: 胆管癌
Name Pinyin: Dan Guan Ai
Name En: Cholangiocarcinoma
Name Latin
Bilingual Status: complete
Disease Type: disease
Umls Disease Type: Neoplastic Process
Disgenet Type: disease
Mesh Class: Digestive System Diseases; NeoplasmsNeoplasms
Do Class: disease of anatomical entity; disease of cellular proliferation
Hpo Class: Neoplasm; Abnormality of the digestive system
Mesh Class Name: Digestive System Diseases; NeoplasmsNeoplasms
Hpo Class Name: Abnormality of the digestive system; Neoplasm
Do Class Name: disease of anatomical entity; disease of cellular proliferation
Disease Definition: Cholangiocarcinoma (CCA) is a biliary tract cancer (BTC, see this term) originating in the epithelium of the biliary tree, either intra or extra hepatic.
Version: v1,v2
Suppressed: No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name

Cholangiocarcinoma

Role

preferred

Name

Bile Duct Carcinoma

Role

preferred

Name

Bile Duct Neoplasms

Role

preferred

Name

Biliary Tract Neoplasm

Role

preferred

Name

Intrahepatic Cholangiocarcinoma

Role

preferred

Name

Adult Cholangiocarcinoma

Role

preferred

Name

Bile Duct Adenocarcinoma

Role

preferred

Name

Biliary Tract Cancer

Role

preferred

Name

Carcinoma of Extrahepatic Bile Duct

Role

preferred

Name

Extrahepatic Cholangiocarcinoma

Role

preferred

Name

Malignant Tumor of Extrahepatic Bile Duct

Role

preferred

Name

Bile Duct Cancer

Role

alias

Name

Biliary Tract Neoplasms

Role

alias

Name

Biliary Tract, Unspecified

Role

alias

Name

CCA

Role

alias

Name

Extrahepatic Bile Duct

Role

alias

Name

Extrahepatic Bile Duct Carcinoma

Role

alias

Name

Intrahepatic Bile Duct Carcinoma

Role

alias

Name

Malignant Neoplasm of Biliary Tract, Unspecified

Role

alias

Name

Malignant Neoplasm of Extrahepatic Bile Duct

Role

alias

Cross References

Trusted external identifiers retained for this final record.

Hpo

HP:0030153HP:0100574

Herb

HBDIS000323HBDIS000328HBDIS003789HBDIS004428HBDIS005096HBDIS007193HBDIS008292HBDIS010778HBDIS011102HBDIS014062HBDIS022172

Me Sh

D001650D001661D018281

Omim

615619

Umls

C0005396C0005426C0206698C0345905C0740277

Icd10

C22.1C24.0C24.8C24.9

Med Dra

1000459310008593

Sym Map

SMDE00207SMDE06412SMDE06422SMDE06431SMDE10040

Do Class

DOID:14566DOID:7

Dis Ge Net

C0005396C0005426C0153453C0206698C0238019C0280725C0345905C0740277C0750952C1370800C3805278

Orphanet

70567

Umls Sty

T191

Hpo Class

HP:0002664HP:0025031

Me Sh Class

C04C06

Etcm Disease

Cholangiocarcinoma

Tcmbank Disease

10449105351449917001171581804218412061321172219293324382552887930

Itcmdb Generated

ITX-DISEASE-24A8EA327C33ITX-DISEASE-381D5DC9061AITX-DISEASE-5A733BC2D4E7ITX-DISEASE-AE42EEC0297CITX-DISEASE-B974892DBAE4ITX-DISEASE-DCEE47CA1C0B

Attributes

Merged source attributes and domain-specific metadata.

Version

v1,v2v2

Suppress

Page Title

Disease Cholangiocarcinoma Details page

Do Class Name

disease of anatomical entity; disease of cellular proliferation

Disease Type

diseasegroup

Hpo Class Name

Abnormality of the digestive system; Neoplasm

Do Disease Class

disease of anatomical entity; disease of cellular proliferation

Hpo Disease Class

Neoplasm; Abnormality of the digestive system

Umls Disease Type

Neoplastic Process

Basic Information

Disease Name

Cholangiocarcinoma

Global Category

Cancer diseases;Rare diseases

Anatomical Category

Liver diseases;Nephrological diseases;Skin diseases

Disease Definition

Cholangiocarcinoma (CCA) is a biliary tract cancer (BTC, see this term) originating in the epithelium of the biliary tree, either intra or extra hepatic.MSH2017_2016_08_12:Tumors or cancer in the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.|HPO2016_07_04:Tumor or cancer originating in the biliary tract. []|HPO2016_07_04:A tumor (abnormal growth of tissue) of the biliary system. [HPO:probinson]|CSP2006:new abnormal biliary tract tissue that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease; includes neoplasms of the bile ducts and the gallbladder.NCI2016_02D:A benign or malignant neoplasm that affects the intrahepatic or extrahepatic bile ducts. Representative examples of benign neoplasms include bile duct adenoma and extrahepatic bile duct lipoma. Representative examples of malignant neoplasms include intrahepatic and extrahepatic cholangiocarcinoma.|MSH2017_2016_08_12:Tumors or cancer of the BILE DUCTS.NCI2016_CDISC_1602D:A malignant neoplasm of the liver arising from/comprising cells resembling those of bile ducts.|NCI2016_02D:A carcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree. Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor.|MSH2017_2016_08_12:A carcinoma that originates in the intrahepatic bile duct epithelium of the intrahepatic biliary tree. Malignant lesions are solid, nodular, and grayish. Most cases are adenocarcinomas. Somatic mutations in BAP1, ARID1A, PBRM1, IDH1, and IDH2 genes have been identified. OMIM: 615619NCI2016_NCI-GLOSS_1602D:Cancer that forms in a bile duct. A bile duct is a tube that carries bile (fluid made by the liver that helps digest fat) between the liver and gallbladder and the intestine. Bile ducts include the common hepatic, cystic, and common bile ducts. Bile duct cancer may be found inside the liver (intrahepatic) or outside the liver (extrahepatic).|NCI2016_02D:A malignant tumor arising from the epithelium of the intrahepatic or extrahepatic bile duct. Carcinomas that arise from the intrahepatic bile ducts and the hepatic ducts are called cholangiocarcinomas and are almost always adenocarcinomas. Carcinomas that arise from the extrahepatic bile ducts are adenocarcinomas, adenosquamous carcinomas, squamous cell carcinomas, small cell carcinomas, or mucoepidermoid carcinomas.|MEDLINEPLUS_20151021:Your liver makes a substance called bile that helps with digestion. Your <a href='https://www.nlm.nih.gov/medlineplus/gallbladderdiseases.html'>gallbladder</a> stores it until you need it to digest fat. Then your gallbladder pushes the bile into tubes called <a href='https://www.nlm.nih.gov/medlineplus/bileductdiseases.html'>bile ducts</a>. They carry the bile to your small intestine. Bile duct cancer is rare. It can happen in the part of the bile duct that is outside or inside the liver. Cancer of the bile duct outside of the liver is much more common. Risk factors include inflammation of the bile duct, older age, some liver diseases, and exposure to certain chemicals. Symptoms can include <ul> <li>Jaundice</li> <li>Itchy skin</li> <li>Fever</li> <li>Abdominal pain</li> <li>Weight loss</li> </ul> Treatments include surgery, radiation therapy, and chemotherapy.

Me Sh Disease Class

Digestive System Diseases; NeoplasmsNeoplasms

Dis Ge Net Disease Type

diseasegroup

Disease Class Name Me Sh

Digestive System Diseases; NeoplasmsNeoplasms

Umls Semantic Type Name

Neoplastic Process