DiseaseID 3422
Barrett食管
disease
NCI2016_02D:A malignant tumor with glandular differentiation arising predominantly from Barrett mucosa in the lower third of the esophagus. Rare examples of esophageal adenocarcinoma deriving from ectopic gastric mucosa
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Disease: 1Experiment: 5Symptom: 3Target: 24Links: 32
Arranging relationship network...
Record Fields
Scalar fields from the final disease record.
- Disease Id
- 3422
- Core Entity Id
- 59627
- Source Entity Count
- 1
- Preferred Name
- Barrett Esophagus
- Name Cn
- Barrett食管
- Name Pinyin
- Barrett Shi Guan
- Name En
- Barrett Esophagus
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Disease or Syndrome
- Disgenet Type
- disease
- Mesh Class
- Digestive System Diseases; Neoplasms
- Do Class
- disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
- Hpo Class
- Neoplasm; Abnormality of the digestive system
- Mesh Class Name
- Digestive System Diseases; Neoplasms
- Hpo Class Name
- Abnormality of the digestive system; Neoplasm
- Do Class Name
- disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
- Disease Definition
- NCI2016_02D:A malignant tumor with glandular differentiation arising predominantly from Barrett mucosa in the lower third of the esophagus. Rare examples of esophageal adenocarcinoma deriving from ectopic gastric mucosa in the upper esophagus have also been reported. Grossly, esophageal adenocarcinomas are similar to esophageal squamous cell carcinomas. Microscopically, adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. The prognosis is poor.
- Version
- v1,v2
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Barrett Esophagus
Role
preferred
Name
Adenocarcinoma Of Esophagus
Role
preferred
Name
Barrett Epithelium
Role
preferred
Name
Barrett'S Esophagus Without Dysplasia
Role
preferred
Name
BARRETT METAPLASIA
Role
alias
Name
Barret Syndrome
Role
alias
Name
Barrett'S Esophagus
Role
alias
Name
Endobrachyesophagus
Role
alias
Name
Esophagus Adenocarcinoma
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0100580
Herb
HBDIS000302HBDIS007094HBDIS012825HBDIS020091
Me Sh
D001471
Omim
614266
Umls
C0004763C0279628
Sym Map
SMDE03322SMDE05472
Do Class
DOID:14566DOID:7
Dis Ge Net
C0004763C0279628C1258085C2887643
Umls Sty
T047T191
Hpo Class
HP:0002664HP:0025031
Me Sh Class
C04C06
Etcm Disease
Barrett Esophagus
Tcmbank Disease
22941279022927320609467
Itcmdb Generated
ITX-DISEASE-2BA7A8492DEBITX-DISEASE-A4BD8E3F3D89ITX-DISEASE-CA3F2F3AB97C
Attributes
Merged source attributes and domain-specific metadata.
Version
v1,v2v2
Suppress
0
Page Title
Disease Barrett Esophagus Details page
Do Class Name
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
Disease Type
disease
Hpo Class Name
Abnormality of the digestive system; Neoplasm
Do Disease Class
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
Hpo Disease Class
Neoplasm; Abnormality of the digestive system
Umls Disease Type
Disease or SyndromeNeoplastic Process
Basic Information
Disease Name
Barrett Esophagus
Global Category
Cancer diseases;Genetic diseases;Rare diseases
Anatomical Category
Gastrointestinal Diseases;Liver diseases
Disease Definition
NCI2016_02D:A malignant tumor with glandular differentiation arising predominantly from Barrett mucosa in the lower third of the esophagus. Rare examples of esophageal adenocarcinoma deriving from ectopic gastric mucosa in the upper esophagus have also been reported. Grossly, esophageal adenocarcinomas are similar to esophageal squamous cell carcinomas. Microscopically, adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. The prognosis is poor.NCI2016_NCI-GLOSS_1602D:A condition in which the cells lining the lower part of the esophagus have changed or been replaced with abnormal cells that could lead to cancer of the esophagus. The backing up of stomach contents (reflux) may irritate the esophagus and, over time, cause Barrett's esophagus.|NCI2016_02D:Esophageal lesion lined with columnar metaplastic epithelium which is flat or villiform. Barrett epithelium is characterized by two different types of cells: goblet cells and columnar cells. The symptomatology of Barrett esophagus is that of gastro-esophageal reflux. It is the precursor of most esophageal adenocarcinomas. (WHO)|MSH2017_2016_08_12:A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.|HPO2016_07_04:An abnormal change (metaplasia) in the cells of the inferior portion of the esophagus. The normal squamous epithelium lining of the esophagus is replaced by metaplastic columnar epithelium. Columnar epithelium refers to a cell type that is typically found in more distal parts of the gastrointestinal system. [HPO:sdoelken]|CSP2006:syndrome including peptic ulcer of the lower esophagus, often with stricture, due to the presence of columnar lined epithelium, which may contain functional mucous cells, parietal cells, or chief cells in the esophagus instead of normal squamous cell epithelium; sometimes pre-malignant, followed by esophageal adenocarcinoma.
Me Sh Disease Class
Digestive System Diseases; Neoplasms
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Digestive System Diseases; Neoplasms
Umls Semantic Type Name
Disease or SyndromeNeoplastic Process