ITCMDBv1
DiseaseID 3295

再生障碍性贫血

disease

NCI2016_NICHD_1602D:Abnormally low levels of red blood cells, white blood cells, and platelets in the blood due to insufficient production by the bone marrow.|NCI2016_NCI-GLOSS_1602D:A condition in which the bone marrow

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Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.

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Disease: 1Experiment: 1Herb: 3Target: 24Links: 28
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Record Fields

Scalar fields from the final disease record.

Disease Id
3295
Core Entity Id
59483
Source Entity Count
1
Preferred Name
Aplastic Anemia
Name Cn
再生障碍性贫血
Name Pinyin
Zai Sheng Zhang Ai Xing Pin Xue
Name En
Aplastic Anemia
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Disease or Syndrome
Disgenet Type
disease
Mesh Class
Hemic and Lymphatic DiseasesHemic and Lymphatic Diseases; Musculoskeletal Diseases
Do Class
disease of anatomical entity
Hpo Class
Abnormality of blood and blood-forming tissues
Mesh Class Name
Hemic and Lymphatic DiseasesMusculoskeletal Diseases; Hemic and Lymphatic Diseases
Hpo Class Name
Abnormality of blood and blood-forming tissues
Do Class Name
disease of anatomical entity
Disease Definition
NCI2016_NICHD_1602D:Abnormally low levels of red blood cells, white blood cells, and platelets in the blood due to insufficient production by the bone marrow.|NCI2016_NCI-GLOSS_1602D:A condition in which the bone marrow is unable to produce blood cells.|NCI2016_02D:Anemia resulting from bone marrow failure (aplastic or hypoplastic bone marrow). The production of erythroblasts and red cells is markedly decreased, and it may be associated with decreased production of granulocytes (granulocytopenia) and platelets (thrombocytopenia) as well. Aplastic anemia may be idiopathic or secondary due to bone marrow damage by toxins, radiation, or immunologic factors.|MSH2017_2016_08_12:A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.|MEDLINEPLUS_20151021:<p>Aplastic <a href='https://www.nlm.nih.gov/medlineplus/anemia.html'>anemia</a> is a rare but serious blood disorder. If you have it, your <a href='https://www.nlm.nih.gov/medlineplus/bonemarrowdiseases.html'>bone marrow</a> doesn't make enough new blood cells. Causes include</p> <ul> <li>Toxic substances, such as pesticides, arsenic, and benzene</li> <li>Radiation therapy and chemotherapy for cancer</li> <li>Certain medicines</li> <li>Infections such as hepatitis, Epstein-Barr virus, or HIV</li> <li>Autoimmune disorders</li> <li>Certain inherited conditions</li> <li>Pregnancy</li> </ul> <p>In many people, the cause is unknown.</p> <p>Symptoms include fatigue, weakness, dizziness, and shortness of breath. It can cause heart problems such as an <a href='https://www.nlm.nih.gov/medlineplus/arrhythmia.html'>irregular heartbeat</a>, an enlarged heart, and <a href='https://www.nlm.nih.gov/medlineplus/heartfailure.html'>heart failure</a>. You may also have frequent infections and <a href='https://www.nlm.nih.gov/medlineplus/bleeding.html'>bleeding</a>.</p> <p>Your doctor will diagnose aplastic anemia based on your medical and family histories, a physical exam, and test results. Once your doctor knows the cause and severity of the condition, he or she can create a treatment plan for you. Treatments include <a href='https://www.nlm.nih.gov/medlineplus/bloodtransfusionanddonation.html'>blood transfusions</a>, blood and marrow <a href='https://www.nlm.nih.gov/medlineplus/stemcells.html'>stem cell transplants</a>, and medicines.</p> <p >NIH: National Heart, Lung, and Blood Institute</p>|HPO2016_07_04:Aplastic anemia is defined as pancytopenia with a hypocellular marrow. [HPO:probinson, pmid:21239768]|CSP2006:anemia associated with a fatty, hypocellular bone marrow and global dyshematopoiesis; can be idiopathic or due to microbial, metabolic, autoimmune, or other abnormality.
Version
v1,v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Aplastic Anemia
Role
preferred
Name
APLASTIC ANEMIA, SUSCEPTIBILITY TO (finding)
Role
preferred
Name
Aplastic Bone Marrow
Role
preferred
Name
Bone Marrow Depression
Role
preferred
Name
Erythroid Hypoplasia
Role
preferred
Name
Hypoplastic Anemia
Role
preferred
Name
APLASTIC ANEMIA, SUSCEPTIBILITY TO
Role
alias
Name
Anemia, Aplastic
Role
alias
Name
Anemia, Hypoplastic
Role
alias
Name
Aplastic Anaemia, Unspecified
Role
alias
Name
Erythroblastopenia
Role
alias
Name
Erythroid Hypoplasia In The Bone Marrow
Role
alias

Cross References

Trusted external identifiers retained for this final record.

Hpo
HP:0001908HP:0001915HP:0012133
Herb
HBDIS000142HBDIS003601HBDIS004201HBDIS010003HBDIS014038HBDIS019576
Me Sh
D000741
Omim
609135
Umls
C0002874C2684859
Icd10
D61.9
Sym Map
SMDE04154
Do Class
DOID:7
Dis Ge Net
C0002874C0151773C0178416C0542035C1368107C2684859
Umls Sty
T033T047
Hpo Class
HP:0001871
Me Sh Class
C05C15
Etcm Disease
Aplastic Anemia
Tcmbank Disease
11489161611722717470206592280330698970
Itcmdb Generated
ITX-DISEASE-52015B399F18ITX-DISEASE-70467C263513ITX-DISEASE-78D6BE1C8480ITX-DISEASE-BE657634CEFD

Attributes

Merged source attributes and domain-specific metadata.

Version
v1,v2
Suppress
0
Page Title
Disease Aplastic Anemia Details page
Do Class Name
disease of anatomical entity
Disease Type
disease
Hpo Class Name
Abnormality of blood and blood-forming tissues
Do Disease Class
disease of anatomical entity
Hpo Disease Class
Abnormality of blood and blood-forming tissues
Umls Disease Type
Disease or SyndromeFinding
Basic Information
Disease Name
Aplastic Anemia
Global Category
Genetic diseases;Rare diseases
Anatomical Category
Blood diseases;Immune diseases
Disease Definition
NCI2016_NICHD_1602D:Abnormally low levels of red blood cells, white blood cells, and platelets in the blood due to insufficient production by the bone marrow.|NCI2016_NCI-GLOSS_1602D:A condition in which the bone marrow is unable to produce blood cells.|NCI2016_02D:Anemia resulting from bone marrow failure (aplastic or hypoplastic bone marrow). The production of erythroblasts and red cells is markedly decreased, and it may be associated with decreased production of granulocytes (granulocytopenia) and platelets (thrombocytopenia) as well. Aplastic anemia may be idiopathic or secondary due to bone marrow damage by toxins, radiation, or immunologic factors.|MSH2017_2016_08_12:A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.|MEDLINEPLUS_20151021:<p>Aplastic <a href='https://www.nlm.nih.gov/medlineplus/anemia.html'>anemia</a> is a rare but serious blood disorder. If you have it, your <a href='https://www.nlm.nih.gov/medlineplus/bonemarrowdiseases.html'>bone marrow</a> doesn't make enough new blood cells. Causes include</p> <ul> <li>Toxic substances, such as pesticides, arsenic, and benzene</li> <li>Radiation therapy and chemotherapy for cancer</li> <li>Certain medicines</li> <li>Infections such as hepatitis, Epstein-Barr virus, or HIV</li> <li>Autoimmune disorders</li> <li>Certain inherited conditions</li> <li>Pregnancy</li> </ul> <p>In many people, the cause is unknown.</p> <p>Symptoms include fatigue, weakness, dizziness, and shortness of breath. It can cause heart problems such as an <a href='https://www.nlm.nih.gov/medlineplus/arrhythmia.html'>irregular heartbeat</a>, an enlarged heart, and <a href='https://www.nlm.nih.gov/medlineplus/heartfailure.html'>heart failure</a>. You may also have frequent infections and <a href='https://www.nlm.nih.gov/medlineplus/bleeding.html'>bleeding</a>.</p> <p>Your doctor will diagnose aplastic anemia based on your medical and family histories, a physical exam, and test results. Once your doctor knows the cause and severity of the condition, he or she can create a treatment plan for you. Treatments include <a href='https://www.nlm.nih.gov/medlineplus/bloodtransfusionanddonation.html'>blood transfusions</a>, blood and marrow <a href='https://www.nlm.nih.gov/medlineplus/stemcells.html'>stem cell transplants</a>, and medicines.</p> <p >NIH: National Heart, Lung, and Blood Institute</p>|HPO2016_07_04:Aplastic anemia is defined as pancytopenia with a hypocellular marrow. [HPO:probinson, pmid:21239768]|CSP2006:anemia associated with a fatty, hypocellular bone marrow and global dyshematopoiesis; can be idiopathic or due to microbial, metabolic, autoimmune, or other abnormality.
Me Sh Disease Class
Hemic and Lymphatic DiseasesHemic and Lymphatic Diseases; Musculoskeletal Diseases
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Hemic and Lymphatic DiseasesMusculoskeletal Diseases; Hemic and Lymphatic Diseases
Umls Semantic Type Name
Disease or SyndromeFinding