DiseaseID 27538

肉毒中毒

Botulisms

NCI2016_02D:A serious bacterial infection caused by botulinum toxin which is produced by Clostridium botulinum. Patients are infected usually by ingestion of contaminated food or wound contamination. It leads to muscle p

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Disease: 1Symptom: 12Target: 12Links: 24
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Record Fields

Scalar fields from the final disease record.

Disease Id
27538
Core Entity Id
120106
Source Entity Count
1
Preferred Name
Botulisms
Name Cn
肉毒中毒
Name Pinyin
Rou Du Zhong Du
Name En
Botulisms
Name Latin
Bilingual Status
complete
Disease Type
Umls Disease Type
Disgenet Type
Mesh Class
Do Class
Hpo Class
Mesh Class Name
Hpo Class Name
Do Class Name
Disease Definition
NCI2016_02D:A serious bacterial infection caused by botulinum toxin which is produced by Clostridium botulinum. Patients are infected usually by ingestion of contaminated food or wound contamination. It leads to muscle paralysis which may result in respiratory failure.|MSH2017_2016_08_12:A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)|MEDLINEPLUS_20151021:<p>Botulism is a rare but serious illness. The cause is a toxin (poison) made by a bacterium called Clostridium botulinum. It occurs naturally in soil. </p> <p>There are several kinds of botulism. <a href='https://www.nlm.nih.gov/medlineplus/foodborneillness.html'>Foodborne</a> botulism comes from eating foods contaminated with the toxin. Wound botulism happens when a wound infected with the bacteria makes the toxin. It is more common in heroin users. Infant botulism happens when a baby consumes the spores of the bacteria from soil or honey. All forms can be deadly and are medical emergencies.</p> <p>Symptoms include double or blurred vision, drooping eyelids, slurred speech, difficulty swallowing, dry mouth, and muscle weakness. Treatment may include antitoxins, intensive medical care, or surgery of infected wounds.</p> <p>To prevent botulism:</p> <ul> <li> Be very careful when canning foods at home</li> <li> Do not let babies eat honey</li> <li>Get prompt medical care for infected wounds</li> </ul> <p >Centers for Disease Control and Prevention</p>|CSP2006:disease caused by potent protein neurotoxins produced by Clostridium botulinum, which interfere with the presynaptic release of acetylcholine at the neuromuscular junction; clinical features include abdominal pain, vomiting, acute paralysis, blurred vision and diplopia; botulism may be classified into several subtypes such as food borne, infant, wound, and others.|CHV2011_02:a neurologic disease caused by the toxin of the bacteria called Clostridium botulinum|CHV2011_02:a neurologic disease caused by the toxin of the bacteria called Clostridium botulinum
Version
v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Botulisms
Role
preferred
Source
SymMap_v2
Preferred
Yes

Cross References

Trusted external identifiers retained for this final record.

Umls
C0006057
Icd10
A05.1
Sym Map
SMDE06544

Attributes

Merged source attributes and domain-specific metadata.

Version
v2
Suppress
0
Disease Definition
NCI2016_02D:A serious bacterial infection caused by botulinum toxin which is produced by Clostridium botulinum. Patients are infected usually by ingestion of contaminated food or wound contamination. It leads to muscle paralysis which may result in respiratory failure.|MSH2017_2016_08_12:A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)|MEDLINEPLUS_20151021:<p>Botulism is a rare but serious illness. The cause is a toxin (poison) made by a bacterium called Clostridium botulinum. It occurs naturally in soil. </p> <p>There are several kinds of botulism. <a href='https://www.nlm.nih.gov/medlineplus/foodborneillness.html'>Foodborne</a> botulism comes from eating foods contaminated with the toxin. Wound botulism happens when a wound infected with the bacteria makes the toxin. It is more common in heroin users. Infant botulism happens when a baby consumes the spores of the bacteria from soil or honey. All forms can be deadly and are medical emergencies.</p> <p>Symptoms include double or blurred vision, drooping eyelids, slurred speech, difficulty swallowing, dry mouth, and muscle weakness. Treatment may include antitoxins, intensive medical care, or surgery of infected wounds.</p> <p>To prevent botulism:</p> <ul> <li> Be very careful when canning foods at home</li> <li> Do not let babies eat honey</li> <li>Get prompt medical care for infected wounds</li> </ul> <p >Centers for Disease Control and Prevention</p>|CSP2006:disease caused by potent protein neurotoxins produced by Clostridium botulinum, which interfere with the presynaptic release of acetylcholine at the neuromuscular junction; clinical features include abdominal pain, vomiting, acute paralysis, blurred vision and diplopia; botulism may be classified into several subtypes such as food borne, infant, wound, and others.|CHV2011_02:a neurologic disease caused by the toxin of the bacteria called Clostridium botulinum|CHV2011_02:a neurologic disease caused by the toxin of the bacteria called Clostridium botulinum