DiseaseID 26094

婴儿型纹状体黑质变性

Striatonigral Degeneration, Infantile

SNOMEDCT_US_2016_09_01:Comprises of several syndromes of bilateral symmetric spongy degeneration of the caudate nucleus, putamen and globus pallidus with characteristics of developmental regression, choreoathetosis and d

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Disease: 1Symptom: 3Target: 4Links: 7
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Record Fields

Scalar fields from the final disease record.

Disease Id
26094
Core Entity Id
118662
Source Entity Count
1
Preferred Name
Striatonigral Degeneration, Infantile
Name Cn
婴儿型纹状体黑质变性
Name Pinyin
Ying Er Xing Wen Zhuang Ti Hei Zhi Bian Xing
Name En
Striatonigral Degeneration, Infantile
Name Latin
Bilingual Status
complete
Disease Type
Umls Disease Type
Disgenet Type
Mesh Class
Do Class
Hpo Class
Mesh Class Name
Hpo Class Name
Do Class Name
Disease Definition
SNOMEDCT_US_2016_09_01:Comprises of several syndromes of bilateral symmetric spongy degeneration of the caudate nucleus, putamen and globus pallidus with characteristics of developmental regression, choreoathetosis and dystonia progressing to spastic quadriparesis. Can be familial or sporadic. The familial form has an insidious onset and a slowly progressive downhill course, while the sporadic form is associated with abrupt neurologic dysfunction following an acute systemic febrile illness such as a mycoplasma, measles or streptococcus infection. Familial disease can be inherited as an autosomal recessive or mitochondrial disorder.|JABL99:Degeneration of the caudate nucleus, putamen, and sometimes globus pallidus associated with choreoathetosis, abnormal eye movements, seizures, and mental retardation. Symptoms usually appear after a severe infectious disease.
Version
v1,v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Striatonigral Degeneration, Infantile
Role
preferred
Source
SymMap_v2
Preferred
Yes

Cross References

Trusted external identifiers retained for this final record.

Umls
C0795996
Sym Map
SMDE01922

Attributes

Merged source attributes and domain-specific metadata.

Version
v1,v2
Suppress
0
Disease Definition
SNOMEDCT_US_2016_09_01:Comprises of several syndromes of bilateral symmetric spongy degeneration of the caudate nucleus, putamen and globus pallidus with characteristics of developmental regression, choreoathetosis and dystonia progressing to spastic quadriparesis. Can be familial or sporadic. The familial form has an insidious onset and a slowly progressive downhill course, while the sporadic form is associated with abrupt neurologic dysfunction following an acute systemic febrile illness such as a mycoplasma, measles or streptococcus infection. Familial disease can be inherited as an autosomal recessive or mitochondrial disorder.|JABL99:Degeneration of the caudate nucleus, putamen, and sometimes globus pallidus associated with choreoathetosis, abnormal eye movements, seizures, and mental retardation. Symptoms usually appear after a severe infectious disease.