DiseaseID 22226

IgG缺乏症

Igg Deficiency

Relationship Network

Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.

Click a node to open it in a new tab

Disease: 1Symptom: 1Target: 12Links: 13

Arranging relationship network...

Record Fields

Scalar fields from the final disease record.

Disease Id: 22226
Core Entity Id: 103512
Source Entity Count: 1
Preferred Name: Igg Deficiency
Name Cn: IgG缺乏症
Name Pinyin: Igg Que Fa Zheng
Name En: Igg Deficiency
Name Latin
Bilingual Status: complete
Disease Type
Umls Disease Type
Disgenet Type
Mesh Class
Do Class
Hpo Class
Mesh Class Name
Hpo Class Name
Do Class Name
Disease Definition: NCI2016_02D:A classification of dysgammaglobulinemias characterized by low or undetectable serum levels of one of the four immunoglobulin class G (IgG) subclasses. Selective IgG1 deficiency is rare and primarily decreases the immune response to bacterial protein antigens. Selective IgG2 deficiency is the most common subclass deficiency among children and primarily leads to an inadequate response to bacterial polysaccharide antigens. Selective IgG3 deficiency is the most common subclass deficiency among adults and also primarily lowers the response to bacterial proteins. Selective IgG4 deficiency may be a clinically insignificant developmental variant, as IgG4 is a subclass that is virtually undetectable until the end of the first decade of life. Low levels of any IgG subclass will reduce the immune system's effectiveness and thus the clinical presentation of these diseases is usually recurrent infection, particularly by encapsulated bacteria.|NCI2016_02D:A broad classification of dysgammaglobulinemias characterized by low or undetectable serum levels of immunoglobulin class G (IgG). Deficiencies of IgG present variably according to subclass. IgG deficiencies are typically relative among subclasses and not absolute. Thus even with a given selective IgG subclass deficiency, total IgG levels may still fall within normal range. The clinical course and prognosis is dependent upon the severity of the deficiency and associated morbidity.|MSH2017_2016_08_12:A dysgammaglobulinemia characterized by a deficiency of IMMUNOGLOBULIN G.|HPO2016_07_04:An abnormally decreased level of immunoglobulin IgG in blood. [HPO:probinson]
Version: v2
Suppressed: No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name

Igg Deficiency

Role

preferred

Cross References

Trusted external identifiers retained for this final record.

Umls

C0162539

Sym Map

SMDE09773

Tcmbank Disease

1789

Itcmdb Generated

ITX-DISEASE-374BF91EAD78

Attributes

Merged source attributes and domain-specific metadata.

Version

Suppress

Disease Definition

NCI2016_02D:A classification of dysgammaglobulinemias characterized by low or undetectable serum levels of one of the four immunoglobulin class G (IgG) subclasses. Selective IgG1 deficiency is rare and primarily decreases the immune response to bacterial protein antigens. Selective IgG2 deficiency is the most common subclass deficiency among children and primarily leads to an inadequate response to bacterial polysaccharide antigens. Selective IgG3 deficiency is the most common subclass deficiency among adults and also primarily lowers the response to bacterial proteins. Selective IgG4 deficiency may be a clinically insignificant developmental variant, as IgG4 is a subclass that is virtually undetectable until the end of the first decade of life. Low levels of any IgG subclass will reduce the immune system's effectiveness and thus the clinical presentation of these diseases is usually recurrent infection, particularly by encapsulated bacteria.|NCI2016_02D:A broad classification of dysgammaglobulinemias characterized by low or undetectable serum levels of immunoglobulin class G (IgG). Deficiencies of IgG present variably according to subclass. IgG deficiencies are typically relative among subclasses and not absolute. Thus even with a given selective IgG subclass deficiency, total IgG levels may still fall within normal range. The clinical course and prognosis is dependent upon the severity of the deficiency and associated morbidity.|MSH2017_2016_08_12:A dysgammaglobulinemia characterized by a deficiency of IMMUNOGLOBULIN G.|HPO2016_07_04:An abnormally decreased level of immunoglobulin IgG in blood. [HPO:probinson]