DiseaseID 1903
恶性贫血
disease
NCI2016_NCI-GLOSS_1602D:A type of anemia (low red blood cell count) caused by the body's inability to absorb vitamin B12.|NCI2016_02D:Megaloblastic anemia caused by vitamin B-12 deficiency due to impaired absorption. The
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Disease: 1Symptom: 12Target: 24Links: 36
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 1903
- Core Entity Id
- 2140
- Source Entity Count
- 1
- Preferred Name
- Anemia, Pernicious
- Name Cn
- 恶性贫血
- Name Pinyin
- E Xing Pin Xue
- Name En
- Anemia, Pernicious
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Congenital Abnormality
- Disgenet Type
- disease
- Mesh Class
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic DiseasesFemale Urogenital Diseases and Pregnancy Complications; Nutritional and Metabolic Diseases; Digestive System Diseases; Male Urogenital Diseases; Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic DiseasesHemic and Lymphatic DiseasesNutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
- Do Class
- disease of anatomical entitydisease of metabolism
- Hpo Class
- Abnormality of blood and blood-forming tissues
- Mesh Class Name
- Hemic and Lymphatic DiseasesNutritional and Metabolic Diseases; Hemic and Lymphatic DiseasesPathological Conditions, Signs and Symptoms; Digestive System Diseases; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Hemic and Lymphatic Diseases
- Hpo Class Name
- Abnormality of blood and blood-forming tissues
- Do Class Name
- disease of anatomical entitydisease of metabolism
- Disease Definition
- NCI2016_NCI-GLOSS_1602D:A type of anemia (low red blood cell count) caused by the body's inability to absorb vitamin B12.|NCI2016_02D:Megaloblastic anemia caused by vitamin B-12 deficiency due to impaired absorption. The impaired absorption of vitamin B-12 is secondary to atrophic gastritis and loss of gastric parietal cells.|MSH2017_2016_08_12:A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed)|CSP2006:anemia due to poor intestinal absorption of vitamin B12 caused by defective production of intrinsic factor (a carrier protein) by the gastric mucosa.|CHV2011_02:a decrease in red blood cells that occurs when the body cannot absorb vitamin B12|CHV2011_02:a decrease in red blood cells that occurs when the body cannot absorb vitamin B12|CHV2011_02:a decrease in red blood cells that occurs when the body cannot absorb vitamin B12|CHV2011_02:a decrease in red blood cells that occurs when the body cannot absorb vitamin B12|CHV2011_02:a decrease in red blood cells that occurs when the body cannot absorb vitamin B12
- Version
- v1,v2
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Anemia, Pernicious
Role
preferred
Name
Anemia, Megaloblastic
Role
preferred
Name
Megaloblastic Anemia 1
Role
preferred
Name
Megaloblastic Anemia Due To Dihydrofolate Reductase Deficiency
Role
preferred
Name
Congenital Deficiency of Intrinsic Factor
Role
preferred
Name
Megaloblastic Anemia Due To Inborn Errors of Metabolism
Role
preferred
Name
DHFR DEFICIENCY
Role
alias
Name
ENTEROCYTE COBALAMIN MALABSORPTION
Role
alias
Name
ENTEROCYTE INTRINSIC FACTOR RECEPTOR, DEFECT OF
Role
alias
Name
IGS
Role
alias
Name
IMERSLUND-GRASBECK SYNDROME
Role
alias
Name
MGA1
Role
alias
Name
Megaloblastic Anemia
Role
alias
Name
PERNICIOUS ANEMIA, JUVENILE, DUE TO SELECTIVE INTESTINAL MALABSORPTION OF VITAMIN B12, WITH PROTEINURIA
Role
alias
Name
Pernicious Anemia
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0001889
Herb
HBDIS000153HBDIS000157HBDIS013452HBDIS020786HBDIS027312HBDIS028436
Me Sh
D000749D000752
Omim
170900261100613839
Umls
C0002888C0002892C1306856C3151205
Icd10
D51.0D51.1D53.1
Sym Map
SMDE02403SMDE04339SMDE05851SMDE05852
Do Class
DOID:0014667DOID:7
Dis Ge Net
C0002888C0002892C0340957C1306856C3151205C4551825
Umls Sty
T019T047
Hpo Class
HP:0001871
Me Sh Class
C06C12C13C15C16C18C23
Etcm Disease
Megaloblastic Anemia 1Megaloblastic Anemia Due to Dihydrofolate Reductase Deficiency
Tcmbank Disease
1485217358185652111527057
Itcmdb Generated
ITX-DISEASE-3B5FA43F4942ITX-DISEASE-62A06A089B59
Attributes
Merged source attributes and domain-specific metadata.
Version
v1,v2v2
Suppress
0
Page Title
Disease Megaloblastic Anemia 1 Details pageDisease Megaloblastic Anemia Due to Dihydrofolate Reductase Deficiency Details page
Do Class Name
disease of anatomical entitydisease of metabolism
Disease Type
disease
Hpo Class Name
Abnormality of blood and blood-forming tissues
Do Disease Class
disease of anatomical entitydisease of metabolism
Hpo Disease Class
Abnormality of blood and blood-forming tissues
Umls Disease Type
Congenital AbnormalityDisease or Syndrome
Basic Information
Disease Name
Megaloblastic Anemia 1
Global Category
Genetic diseases;Metabolic diseases;Rare diseases
Anatomical Category
Blood diseases;Gastrointestinal Diseases;Nephrological diseases;Neuronal diseases
Disease Name
Megaloblastic Anemia Due to Dihydrofolate Reductase Deficiency
Global Category
Genetic diseases;Metabolic diseases;Rare diseases
Anatomical Category
Blood diseases;Neuronal diseases
Disease Definition
NCI2016_NCI-GLOSS_1602D:A type of anemia (low red blood cell count) caused by the body's inability to absorb vitamin B12.|NCI2016_02D:Megaloblastic anemia caused by vitamin B-12 deficiency due to impaired absorption. The impaired absorption of vitamin B-12 is secondary to atrophic gastritis and loss of gastric parietal cells.|MSH2017_2016_08_12:A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed)|CSP2006:anemia due to poor intestinal absorption of vitamin B12 caused by defective production of intrinsic factor (a carrier protein) by the gastric mucosa.|CHV2011_02:a decrease in red blood cells that occurs when the body cannot absorb vitamin B12|CHV2011_02:a decrease in red blood cells that occurs when the body cannot absorb vitamin B12|CHV2011_02:a decrease in red blood cells that occurs when the body cannot absorb vitamin B12|CHV2011_02:a decrease in red blood cells that occurs when the body cannot absorb vitamin B12|CHV2011_02:a decrease in red blood cells that occurs when the body cannot absorb vitamin B12NCI2016_NICHD_1602D:A disorder characterized by low red blood cells and/or hemoglobin and abnormally large, immature circulating red blood cells.|NCI2016_02D:Anemia characterized by the presence of unusually large erythroblasts in the bone marrow called megaloblasts. It is usually caused by vitamin B12 or folic acid deficiency. Other causes include toxins and drugs.|MSH2017_2016_08_12:A disorder characterized by the presence of ANEMIA, abnormally large red blood cells (megalocytes or macrocytes), and MEGALOBLASTS.|HPO2016_07_04:Anemia characterized by the presence of erythroblasts that are larger than normal (megaloblasts). [HPO:probinson]|CSP2006:anemias associated with impaired DNA synthesis in bone marrow progenitor cells leading to odd shaped, macrocytic, or dysfunctional erythrocytes; usually caused by B12 or folate deficiency.
Me Sh Disease Class
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic DiseasesFemale Urogenital Diseases and Pregnancy Complications; Nutritional and Metabolic Diseases; Digestive System Diseases; Male Urogenital Diseases; Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic DiseasesHemic and Lymphatic DiseasesNutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Hemic and Lymphatic DiseasesNutritional and Metabolic Diseases; Hemic and Lymphatic DiseasesPathological Conditions, Signs and Symptoms; Digestive System Diseases; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Hemic and Lymphatic Diseases
Umls Semantic Type Name
Disease or Syndrome