DiseaseID 12634
肢端肥大症
disease
Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterized by progressive somatic disfigurement (mainly involving the face and extremities) and systemi
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Disease: 1Herb: 1Symptom: 12Target: 28Links: 41
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 12634
- Core Entity Id
- 70170
- Source Entity Count
- 1
- Preferred Name
- Acromegaly
- Name Cn
- 肢端肥大症
- Name Pinyin
- Zhi Duan Fei Da Zheng
- Name En
- Acromegaly
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Disease or Syndrome
- Disgenet Type
- disease
- Mesh Class
- Endocrine System Diseases; Nervous System Diseases; Musculoskeletal DiseasesNeoplasmsNervous System Diseases; Endocrine System DiseasesNervous System Diseases; Neoplasms; Endocrine System Diseases
- Do Class
- disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
- Hpo Class
- Abnormality of the nervous system; Abnormality of the endocrine systemNeoplasm; Abnormality of the nervous system; Abnormality of the endocrine system
- Mesh Class Name
- Musculoskeletal Diseases; Nervous System Diseases; Endocrine System DiseasesNeoplasmsNeoplasms; Nervous System Diseases; Endocrine System DiseasesNervous System Diseases; Endocrine System Diseases
- Hpo Class Name
- Abnormality of the endocrine system; Abnormality of the nervous systemAbnormality of the endocrine system; Abnormality of the nervous system; Neoplasm
- Do Class Name
- disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
- Disease Definition
- Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterized by progressive somatic disfigurement (mainly involving the face and extremities) and systemi
- Version
- v1
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Acromegaly
Role
preferred
Name
Adenoma, Acidophil
Role
preferred
Name
Growth Hormone-Secreting Pituitary Adenoma
Role
preferred
Name
Pituitary Adenoma Predisposition (Disorder)
Role
preferred
Name
Pituitary Adenoma, Familial Isolated (Disorder)
Role
preferred
Name
Pituitary Adenoma, Growth Hormone-Secreting, 1
Role
preferred
Name
ACTH-Secreting Pituitary Adenoma
Role
preferred
Name
Gigantism And Acromegaly
Role
preferred
Name
Growth Hormone Excess
Role
preferred
Name
Inappropriate ACTH Secretion Syndrome
Role
preferred
Name
PITUITARY ADENOMA 1, MULTIPLE TYPES
Role
preferred
Name
PITUITARY ADENOMA 2, GROWTH HORMONE-SECRETING
Role
preferred
Name
Pituitary-Dependent Cushing'S Disease
Role
preferred
Name
Somatotrophinoma, Familial
Role
preferred
Name
ACROMEGALY DUE TO PITUITARY ADENOMA 1
Role
alias
Name
Acidophil Adenoma
Role
alias
Name
Acral Hypertrophy
Role
alias
Name
Acromegalic Growth
Role
alias
Name
Acromegaly And Pituitary Gigantism
Role
alias
Name
Acth-Producing Pituitary Adenoma
Role
alias
Name
Corticotropin-Secreting Pituitary Adenoma
Role
alias
Name
Cushing Disease
Role
alias
Name
FIPA
Role
alias
Name
FIS
Role
alias
Name
Growth Hormone Secreting Pituitary Adenoma
Role
alias
Name
IFS
Role
alias
Name
ISOLATED FAMILIAL SOMATOTROPINOMA
Role
alias
Name
PAGH1
Role
alias
Name
PAP
Role
alias
Name
PITUITARY ADENOMA PREDISPOSITION
Role
alias
Name
PITUITARY ADENOMA, FAMILIAL ISOLATED
Role
alias
Name
Pituitary Acth Hypersecretion
Role
alias
Name
Pituitary Adenoma 4, Acth-Secreting
Role
alias
Name
Pituitary Corticotropic Cell Adenoma
Role
alias
Name
SOMATOTROPINOMA, FAMILIAL ISOLATED
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0000845HP:0008291
Herb
HBDIS000036HBDIS000059HBDIS004650HBDIS005034HBDIS008361HBDIS008931HBDIS011203HBDIS013429HBDIS018017HBDIS019430HBDIS021443HBDIS022982HBDIS027041
Me Sh
D000172D000239D047748D049912D049913
Omim
102200219090300943
Umls
C0001206C0001433C0346302C1863340C2676191C3489630
Icd10
E22.0E24.0
Med Dra
10000599
Sym Map
SMDE04697SMDE04862SMDE05402SMDE05520SMDE09163SMDE12182SMDE12183SMDE12190
Do Class
DOID:14566DOID:7
Dis Ge Net
C0001206C0001433C0221406C0235986C0346302C0405578C0751220C1306214C1863340C2676191C3489630C4012409C4538355
Orphanet
963
Umls Sty
T033T047T191
Hpo Class
HP:0000707HP:0000818HP:0002664
Me Sh Class
C04C05C10C19
Etcm Disease
Acromegaly
Tcmbank Disease
103471374416527166771755817830180622219270431166715915695009686
Itcmdb Generated
ITX-DISEASE-330F289CDFD7ITX-DISEASE-4CD0711BEE04ITX-DISEASE-CF2742967110ITX-DISEASE-FF0140381893
Attributes
Merged source attributes and domain-specific metadata.
Version
v1v1,v2v2
Suppress
0
Page Title
Disease Acromegaly Details page
Do Class Name
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
Disease Type
diseasephenotype
Hpo Class Name
Abnormality of the endocrine system; Abnormality of the nervous systemAbnormality of the endocrine system; Abnormality of the nervous system; Neoplasm
Do Disease Class
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
Hpo Disease Class
Abnormality of the nervous system; Abnormality of the endocrine systemNeoplasm; Abnormality of the nervous system; Abnormality of the endocrine system
Umls Disease Type
Disease or SyndromeFindingNeoplastic Process
Basic Information
Disease Name
Acromegaly
Global Category
Rare diseases
Anatomical Category
Endocrine diseases;Neuronal diseases;Reproductive diseases
Disease Definition
Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterized by progressive somatic disfigurement (mainly involving the face and extremities) and systemiNCI2016_02D:An adenoma of the anterior lobe of the pituitary gland that produces growth hormone. The vast majority of cases are hormonally functioning and are associated with either gigantism or acromegaly.|MSH2017_2016_08_12:A pituitary tumor that secretes GROWTH HORMONE. In humans, excess HUMAN GROWTH HORMONE leads to ACROMEGALY.NCI2016_02D:An adenoma of the pituitary gland that produces corticotropin. The vast majority of cases are associated with Cushing disease. Clinical manifestations include truncal obesity with thin extremities, thinning of the skin, osteoporosis, and a tendency to bruise easily. Silent or hormonally non-functioning ACTH producing adenomas have also been described. They produce symptoms of a mass-related lesion.|MSH2017_2016_08_12:A pituitary adenoma which secretes ADRENOCORTICOTROPIN, leading to CUSHING DISEASE.|HPO2016_07_04:A type of pituitary adenoma that produces adrenocorticotropic hormone (ACTH). [DDD:spark, HPO:probinson]NCI2016_02D:An epithelial neoplasm of the anterior pituitary gland in which the neoplastic cells stain positive with acidic dyes.|MSH2017_2016_08_12:A benign tumor, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumors may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (Dorland, 27th ed)NCI2016_NICHD_1602D:Cushing's syndrome due to abnormally high secretion of adrenocorticotropic hormone (ACTH) from the pituitary gland.|NCI2016_NCI-GLOSS_1602D:A condition in which there is too much cortisol (a hormone made by the outer layer of the adrenal gland) in the body. In Cushing disease, this happens when an adenoma (benign tumor) in the pituitary gland makes too much adrenocorticotropic hormone (ACTH). This causes the adrenal gland to make too much cortisol. Symptoms include a round face, thin arms and legs, severe fatigue and muscle weakness, high blood pressure and high blood sugar, purple or pink stretch marks on the skin, and weight gain, especially in the abdomen.|NCI2016_02D:Cushing's syndrome due to abnormally high secretion of adrenocorticotropic hormone (ACTH) from the pituitary gland.(NICHD)|MSH2017_2016_08_12:A disease of the PITUITARY GLAND characterized by the excess amount of ADRENOCORTICOTROPIC HORMONE secreted. This leads to hypersecretion of cortisol (HYDROCORTISONE) by the ADRENAL GLANDS resulting in CUSHING SYNDROME.
Me Sh Disease Class
Endocrine System Diseases; Nervous System Diseases; Musculoskeletal DiseasesNeoplasmsNervous System Diseases; Endocrine System DiseasesNervous System Diseases; Neoplasms; Endocrine System Diseases
Dis Ge Net Disease Type
diseasephenotype
Disease Class Name Me Sh
Musculoskeletal Diseases; Nervous System Diseases; Endocrine System DiseasesNeoplasmsNeoplasms; Nervous System Diseases; Endocrine System DiseasesNervous System Diseases; Endocrine System Diseases
Umls Semantic Type Name
Disease or SyndromeFindingNeoplastic Process