Clinical TrialID 985
Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity
NCT01115452
Dentine Hypersensitivity
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Trial: 1Herb: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 985
- Evidence Id
- 985
- Core Evidence Id
- 985
- Source Clinical Trial Id
- 967
- Herb2 Clinical Trial Id
- HBCT000967
- Nct Id
- NCT01115452
- Title
- Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity
- Status
- Completed
- Phase
- Phase 2
- Study Result
- Yes
- Study Condition
- Dentine Hypersensitivity
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
- Intervention
- DRUG: 5% Potassium nitrate|DRUG: 2.5% Potassium nitrate|OTHER: Sterile water
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Double
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 32
- Outcome Measure
- Between Treatment Comparison of the Adjusted Mean Change From Baseline of Response to Evaporative (Air) Stimuli Immediately Following Treatment on Day 5 Using a Visual Analog Scale (VAS) in 5% Potassium Nitrate Solution and 2.5% Potassium Nitrate Solution, Response to a one second application of air from a standard dental unit syringe applied to the surface of hypersensitive tooth. After each stimuli participant rated the intensity of pain on a 100 millimeter VAS, on which 0 represented "no pain" and 100 represented the" worst pain imaginable". Change from baseline was calculated as mean score at the given time point minus mean score at baseline., Baseline and immediately after treatment on Day 5
- Sponsor Collaborator
- GlaxoSmithKline
- Funded By
- INDUSTRY
- Location
- University Park Research Center (UPRC), Fort Wayne, Indiana, 46825, United States
- Other Id
- Z3770633
- Start Date
- 2009-09
- Primary Completion Date
- 2009-10
- Completion Date
- 2009-10
- First Posted
- 2010-05-04
- Results First Posted
- 2015-01-26
- Last Update Posted
- 2015-01-26
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT01115452
- Title Cn
- Title En
- Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity
- Bilingual Status
- semi_complete