Clinical TrialID 982

The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity

NCT01587950

Dentinal Hypersensitivity|Dental Pain

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Record Fields

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Clinical Trial Id
982
Evidence Id
982
Core Evidence Id
982
Source Clinical Trial Id
964
Herb2 Clinical Trial Id
HBCT000964
Nct Id
NCT01587950
Title
The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity
Status
Completed
Phase
Phase 1
Study Result
Yes
Study Condition
Dentinal Hypersensitivity|Dental Pain
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Intervention
DRUG: Potassium Nitrate|DRUG: Placebo
Intervention Allocation
Randomized
Intervention Model
Crossover
Intervention Mask
Double
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
12
Outcome Measure
Adjusted Mean Change From Baseline in Evaporative Sensitivity Pain Response of Hypersensitive Tooth on a Visual Analogue Scale (VAS) Immediately Post Application of 5% KNO3 Solution, 2.5% KNO3 Solution and Sterile Water, Response to a constant jet of air applied to a hypersensitive tooth was evaluated using a 100 millimeter (mm) VAS pain response scale. According to this analog scale, pain response for stimulated tooth ranged from 0 (no pain) to 100 (intense pain). Change from baseline in pain response was calculated using VAS score immediately post treatment., Baseline, immediately post administration of treatment|Adjusted Mean Change From Baseline in Evaporative Sensitivity Pain Response of Hypersensitive Tooth on a VAS, 10 Minutes Post Application of 5% KNO3 Solution, 2.5% KNO3 Solution and Sterile Water, Response to a constant (duration, pressure, temperature, distance from target) jet of air applied to a hypersensitive tooth was evaluated using a 100 mm VAS pain response scale. According to this analog scale, pain response for stimulated tooth ranged from 0 (no pain) to 100 (intense pain). Change from baseline in pain response was calculated using VAS score at 10 minutes post treatment., Baseline, 10 minutes post administration of treatment|Adjusted Mean Change From Baseline in Evaporative Sensitivity Pain Response of Hypersensitive Tooth on a VAS, 20 Minute Post Application of 5% KNO3 Solution, 2.5% KNO3 Solution and Sterile Water, Response to a constant (duration, pressure, temperature, distance from target) jet of air applied to a hypersensitive tooth was evaluated using a 100 mm VAS pain response scale. According to this analog scale, pain response for stimulated tooth ranged from 0 (no pain) to 100 (intense pain). Change from baseline in pain response was calculated using VAS score at 20 minutes post treatment., Baseline, 20 minutes post administration of treatment
Sponsor Collaborator
GlaxoSmithKline
Funded By
INDUSTRY
Location
University Park Research Center (UPRC), Fort Wayne, Indiana, 46825, United States
Other Id
Z3770631
Start Date
2009-02
Primary Completion Date
2009-04
Completion Date
2009-04
First Posted
2012-04-30
Results First Posted
2015-04-28
Last Update Posted
2015-04-28
Study Document
Study Url
https://clinicaltrials.gov/study/NCT01587950
Title Cn
Title En
The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity
Bilingual Status
semi_complete