Clinical TrialID 971

Cymbopogon Citratus Gel as Local Drug Delivery Agent in Reducing Matrix Metalloproteinase-8 Levels Intra-crevicularly in the Treatment of Stage II Periodontitis

NCT05241509

Periodontitis Chronic Generalized Moderate

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Record Fields

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Clinical Trial Id
971
Evidence Id
971
Core Evidence Id
971
Source Clinical Trial Id
952
Herb2 Clinical Trial Id
HBCT000952
Nct Id
NCT05241509
Title
Cymbopogon Citratus Gel as Local Drug Delivery Agent in Reducing Matrix Metalloproteinase-8 Levels Intra-crevicularly in the Treatment of Stage II Periodontitis
Status
Completed
Phase
Phase 4
Study Result
No
Study Condition
Periodontitis Chronic Generalized Moderate
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Intervention
DRUG: Cymbopogon citratus (lemongrass) oil gel
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Double
Intervention Purpose
Treatment
Gender
All
Age
Adult
Enrollment
40
Outcome Measure
Change in periodontal pocket depth, the distance between the gingival margin and depth of probing, baseline and after 12 weeks|Change in clinical attachment loss, the distance between the CEJ and depth of probing, baseline and after 12 weeks|Change in Matrix metalloproteinase-8 level, Human Matrix metalloproteinase-8 level intracrevicularlly by collection of crevicular fluid sample, baseline and after 12 weeks
Sponsor Collaborator
Souzy Kamal
Funded By
OTHER
Location
department of periodontology. Faculty of dentistry. Alexandria University, Alexandria, 21521, Egypt
Other Id
Lemon grass oil
Start Date
2019-07-06
Primary Completion Date
2020-12-14
Completion Date
2021-12-04
First Posted
2022-02-15
Results First Posted
Last Update Posted
2022-02-15
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05241509
Title Cn
Title En
Cymbopogon Citratus Gel as Local Drug Delivery Agent in Reducing Matrix Metalloproteinase-8 Levels Intra-crevicularly in the Treatment of Stage II Periodontitis
Bilingual Status
semi_complete