Clinical TrialID 968
Effect of Artemisia Dracunculus on Glucose Intolerance, Insulin Sensitivity and Insulin Secretion
NCT02330341
Glucose Intolerance
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 968
- Evidence Id
- 968
- Core Evidence Id
- 968
- Source Clinical Trial Id
- 949
- Herb2 Clinical Trial Id
- HBCT000949
- Nct Id
- NCT02330341
- Title
- Effect of Artemisia Dracunculus on Glucose Intolerance, Insulin Sensitivity and Insulin Secretion
- Status
- Completed
- Phase
- Study Result
- Yes
- Study Condition
- Glucose Intolerance
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
- Intervention
- DIETARY_SUPPLEMENT: Artemisia dracunculus|OTHER: Placebo
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Double
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult
- Enrollment
- 24
- Outcome Measure
- Postprandial Glucose Levels at Week 12, Postprandial glucose will be evaluated at baseline and week 12 after a oral glucose tolerance test with enzymatic-colorimetric techniques, Week 12|Fasting Glucose Levels at Week 12, Fasting glucose will be evaluated at baseline and week 12 with enzymatic-colorimetric techniques, Week 12|Glycosylated Hemoglobin at Week 12, Glycosylated hemoglobin will be evaluated at baseline and week 12 by ELISA, Week 12|First Phase of Insulin Secretion at Week 12, The first phase of insulin secretion will be calculated at baseline and week 12 with Stumvoll index. Human studies support the critical physiologic role of the first-phase of insulin secretion in the maintenance of postmeal glucose homeostasis. First phase of insulin secretion was estimated using the Stumvoll index (1283+ 1.829 x insulin 30' - 138.7 x glucose 30' + 3.772 x insulin 0'), the entered values reflect the first phase of insulin secretion, Week 12|Total Insulin Secretion at Week 12, Total insulin secretion will be calculated at baseline and week 12 with insulinogenic index. The insulinogenic index is a ratio that relates enhancement of circulating insulin to the magnitude of the corresponding glycemic stimulus. Total insulin secretion was calculated with the insulinogenic index (ΔABC insulin/ΔABC glucose), the entered values reflect the total insulin secretion, Week 12|Insulin Sensitivity at Week 12, Insulin sensitivity will be calculated at baseline and week 12 with Matsuda index. Matsuda Index value is used to indicate insulin resistance on diabetes. Insulin sensitivity was calculated with Matsuda index \[10,000 / √glucose 0' x insulin 0') (mean glucose oral glucose tolerance test (OGTT) x mean insulin OGTT)\]. The entered values reflect the insulin sensitivity, Week 12
- Sponsor Collaborator
- University of Guadalajara
- Funded By
- OTHER
- Location
- Manuel González Ortiz, Guadalajara, Jalisco, 44140, Mexico
- Other Id
- GI-ESTRAGON
- Start Date
- 2014-12
- Primary Completion Date
- 2015-06
- Completion Date
- 2015-07
- First Posted
- 2015-01-01
- Results First Posted
- 2020-10-08
- Last Update Posted
- 2020-10-08
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT02330341
- Title Cn
- Title En
- Effect of Artemisia Dracunculus on Glucose Intolerance, Insulin Sensitivity and Insulin Secretion
- Bilingual Status
- semi_complete