Clinical TrialID 91

Impacts of Lentils on Metabolism and Inflammation

NCT04283448

Hypertriglyceridemia|Inflammation|Waist, Hypertriglyceridemic

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Record Fields

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Clinical Trial Id
91
Evidence Id
91
Core Evidence Id
91
Source Clinical Trial Id
86
Herb2 Clinical Trial Id
HBCT000086
Nct Id
NCT04283448
Title
Impacts of Lentils on Metabolism and Inflammation
Status
Completed
Phase
Study Result
No
Study Condition
Hypertriglyceridemia|Inflammation|Waist, Hypertriglyceridemic
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Intervention
BEHAVIORAL: Dietary Lentil|BEHAVIORAL: Control
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Intervention Purpose
Prevention
Gender
All
Age
Adult, Older_Adult
Enrollment
38
Outcome Measure
Postprandial Serum Triglyceride Response to High-fat Meal, Area under the curve for triglyceride concentration after consuming a meal containing 50 g of fat, 12 weeks|Peak Serum Triglyceride Response to High-fat Meal, Greatest change in triglyceride concentration after consuming a meal containing 50 g of fat, 12 weeks|Postprandial Serum Inflammatory Cytokine (tumor necrosis factor-alpha, interleukin-(IL)1beta, IL-6, IL-10, IL-17, IL-23, interferon-gamma, and granulocyte macrophage-colony stimulating factor; all in pg/ml) Response to High-fat Meal, Area under the curve for inflammatory cytokine (tumor necrosis factor-alpha, interleukin-(IL)1beta, IL-6, IL-10, IL-17, IL-23, interferon-gamma, and granulocyte macrophage-colony stimulating factor; all in pg/ml) concentrations after consuming a meal containing 50 g of fat, 12 weeks|Peak Cytokine (tumor necrosis factor-alpha, interleukin-(IL)1beta, IL-6, IL-10, IL-17, IL-23, interferon-gamma, and granulocyte macrophage-colony stimulating factor; all in pg/ml) Response to High-fat Meal, Greatest change in inflammatory cytokine (tumor necrosis factor-alpha, interleukin-(IL)1beta, IL-6, IL-10, IL-17, IL-23, interferon-gamma, and granulocyte macrophage-colony stimulating factor; all in pg/ml) concentration after consuming a meal containing 50 g of fat, 12 weeks|Gut Microbiome Composition, Relative abundance (operational taxonomic units/10,000 reads) of microbial taxa measured from fecal samples, 12 weeks|Postprandial Serum Metabolite (untargeted) Response to High-fat Meal, Changes in concentrations of metabolites measured with untargeted liquid chromatography mass spectrometry (LCMS) metabolomic analysis after consuming a meal containing 50 g of fat, 12 weeks|Fasting serum triglycerides, Concentration of triglycerides in the serum after an overnight fast, 12 weeks|Fasting inflammatory cytokine (tumor necrosis factor-alpha, interleukin-(IL)1beta, IL-6, IL-10, IL-17, IL-23, interferon-gamma, and granulocyte macrophage-colony stimulating factor; all in pg/ml) levels, Concentration of inflammatory cytokines (tumor necrosis factor-alpha, interleukin-(IL)1beta, IL-6, IL-10, IL-17, IL-23, interferon-gamma, and granulocyte macrophage-colony stimulating factor; all in pg/ml) in the serum after an overnight fast, 12 weeks|Fasting serum metabolites (untargeted), Concentration of metabolites in the serum after an overnight fast, 12 weeks
Sponsor Collaborator
Montana State University
Funded By
OTHER
Location
Nutrition Research Laboratory, Bozeman, Montana, 59717, United States
Other Id
58-3060-9-040
Start Date
2020-05-22
Primary Completion Date
2023-11-19
Completion Date
2023-11-19
First Posted
2020-02-25
Results First Posted
Last Update Posted
2023-11-21
Study Document
Study Url
https://clinicaltrials.gov/study/NCT04283448
Title Cn
Title En
Impacts of Lentils on Metabolism and Inflammation
Bilingual Status
semi_complete