Clinical TrialID 8464

Smell in COVID-19 and Efficacy of Nasal Theophylline (SCENT 3)

NCT05947643

COVID-19

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Record Fields

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Clinical Trial Id
8464
Evidence Id
8464
Core Evidence Id
8464
Source Clinical Trial Id
8462
Herb2 Clinical Trial Id
HBCT008462
Nct Id
NCT05947643
Title
Smell in COVID-19 and Efficacy of Nasal Theophylline (SCENT 3)
Status
Active_Not_Recruiting
Phase
Phase 2
Study Result
No
Study Condition
COVID-19
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Intervention
DRUG: theophylline|DRUG: Placebo
Intervention Allocation
Randomized
Intervention Model
Single_Group
Intervention Mask
Double
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
41
Outcome Measure
Clinical Global Impression Scale (CGI), The CGI is a 3-item observer-rated scale that measures illness severity (CGIS), global improvement or change (CGIC). The CGI is rated on a 7-point scale, with the severity of illness scale using a range of responses from 1 (normal) through to 7 (amongst the most severely ill patients). CGI scores range from 1 (very much improved) through to 7 (very much worse). We will measure the response rate defined as the number of participants self-reporting minimal change or larger in the Clinical Global Impression Scale (CGI) scale, divided by the number of participants in each group., Week 6 and week 12 of treatment
Sponsor Collaborator
Washington University School of Medicine
Funded By
OTHER
Location
Washington University School of Medicine, Saint Louis, Missouri, 63110, United States
Other Id
202209062
Start Date
2022-11-22
Primary Completion Date
2024-04-24
Completion Date
2024-08-04
First Posted
2023-07-17
Results First Posted
Last Update Posted
2024-07-10
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05947643
Title Cn
Title En
Smell in COVID-19 and Efficacy of Nasal Theophylline (SCENT 3)
Bilingual Status
semi_complete