Clinical TrialID 8393

The Efficacy of Papaverine to Prevent Radial Artery Spasm During Transradial Cerebral Angiography

NCT05861765

Radial Artery Spasm

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Record Fields

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Clinical Trial Id
8393
Evidence Id
8393
Core Evidence Id
8393
Source Clinical Trial Id
8391
Herb2 Clinical Trial Id
HBCT008391
Nct Id
NCT05861765
Title
The Efficacy of Papaverine to Prevent Radial Artery Spasm During Transradial Cerebral Angiography
Status
Recruiting
Phase
Phase 2
Study Result
No
Study Condition
Radial Artery Spasm
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Intervention
DRUG: Papaverine Hydrochloride|DRUG: normal saline
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Quadruple
Intervention Purpose
Prevention
Gender
All
Age
Adult, Older_Adult
Enrollment
240
Outcome Measure
The incidence of RAS, The primary outcome of this trial is to evaluate the incidence of RAS during surgery. The operator assessed RAS on the basis of a questionnaire addressing the following five signs: persistent forearm pain, pain response on catheter manipulation, pain response to introducer withdrawal, difficult catheter manipulation after being "trapped" by the radial artery with considerable resistance on withdrawal of the introducer. RAS was considered to be indicated by the presence of at least 2 of these 5 signs or by the presence of just 1 when the operator considered it necessary to administer other spasmolytic agent., Intraprocedural: From procedure start to application of radial band. Approximate time 30 to 90 minutes.
Sponsor Collaborator
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Funded By
OTHER
Location
Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510120, China
Other Id
20230421
Start Date
2023-05-24
Primary Completion Date
2023-09-30
Completion Date
2023-10-30
First Posted
2023-05-17
Results First Posted
Last Update Posted
2023-06-12
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05861765
Title Cn
Title En
The Efficacy of Papaverine to Prevent Radial Artery Spasm During Transradial Cerebral Angiography
Bilingual Status
semi_complete