Clinical TrialID 8254

Gut Microbial Metabolites Inosine Combined With PD-1/PD-L1 Inhibitor for Patients With Malignant Advanced Solid Tumors

NCT05809336

Advanced Solid Tumor

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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
8254
Evidence Id
8254
Core Evidence Id
8254
Source Clinical Trial Id
8252
Herb2 Clinical Trial Id
HBCT008252
Nct Id
NCT05809336
Title
Gut Microbial Metabolites Inosine Combined With PD-1/PD-L1 Inhibitor for Patients With Malignant Advanced Solid Tumors
Status
Completed
Phase
Phase 2|Phase 3
Study Result
No
Study Condition
Advanced Solid Tumor
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Intervention
DRUG: Inosine 0.2g orally 3 times/day|DRUG: PD-1/PD-L1 inhibitor ,chemotherapy/targeting
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
172
Outcome Measure
overall survival (OS), Time from randomization grouping to death from any cause, 36 months|progression-free survival (PFS), Time from randomization grouping to the first recorded disease progression or death from any cause, 36 months
Sponsor Collaborator
Beijing Friendship Hospital
Funded By
OTHER
Location
Qin li, Beijing, Beijing, 100029, China
Other Id
Beijing inosine
Start Date
2019-05-01
Primary Completion Date
2022-10-31
Completion Date
2022-10-31
First Posted
2023-04-12
Results First Posted
Last Update Posted
2023-04-12
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05809336
Title Cn
Title En
Gut Microbial Metabolites Inosine Combined With PD-1/PD-L1 Inhibitor for Patients With Malignant Advanced Solid Tumors
Bilingual Status
semi_complete