Clinical TrialID 8248

Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance

NCT05852730

Motion Sickness, Space|Motion Simulation|Parabolic Flight

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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
8248
Evidence Id
8248
Core Evidence Id
8248
Source Clinical Trial Id
8246
Herb2 Clinical Trial Id
HBCT008246
Nct Id
NCT05852730
Title
Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance
Status
Recruiting
Phase
Phase 2
Study Result
No
Study Condition
Motion Sickness, Space|Motion Simulation|Parabolic Flight
Study Type
Interventional
Study Design
Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Intervention
DRUG: DPI-386 Nasal Gel|DRUG: Other (e.g., promethazine, meclizine)
Intervention Allocation
Non_Randomized
Intervention Model
Parallel
Intervention Mask
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
80
Outcome Measure
Motion sickness (MS) symptoms using Pensacola Diagnostic Index (PDI) nausea scale., The maximum nausea score (from 0 = none to 3 = severe) will be recorded once for each of the first three inflight days and once for each of the first three postflight days, or once per operational setting not involving spaceflight (e.g., once per simulation or parabolic flight)., 1 week
Sponsor Collaborator
Repurposed Therapeutics, Inc.|National Aeronautics and Space Administration (NASA)
Funded By
INDUSTRY
Location
NASA Johnson Space Center Neuroscience Laboratory, Houston, Texas, 77058, United States
Other Id
NASA 0354 (Aim 2)
Start Date
2021-08-10
Primary Completion Date
2026-09
Completion Date
2026-09
First Posted
2023-05-10
Results First Posted
Last Update Posted
2024-05-16
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05852730
Title Cn
Title En
Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance
Bilingual Status
semi_complete