Clinical TrialID 8244

Cysteamine Compared to Hydroquinone in Melasma

NCT05969587

Melasma

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Record Fields

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Clinical Trial Id
8244
Evidence Id
8244
Core Evidence Id
8244
Source Clinical Trial Id
8242
Herb2 Clinical Trial Id
HBCT008242
Nct Id
NCT05969587
Title
Cysteamine Compared to Hydroquinone in Melasma
Status
Completed
Phase
Phase 3
Study Result
No
Study Condition
Melasma
Study Type
Interventional
Study Design
Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Intervention
COMBINATION_PRODUCT: 5% cysteamine cream|COMBINATION_PRODUCT: hydroquinone cream group
Intervention Allocation
Non_Randomized
Intervention Model
Parallel
Intervention Mask
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
28
Outcome Measure
Change of Baseline Melasma Area and Severity Index (MASI) scores, MASI scores were computed according to the formula proposed by Kimbrough-Green et al. (1994) , whereby the surface area is graded as 0 (no involvement), 1 (\< 10% involvement), 2 (10-29% involvement), 3 (30-49% involvement), 4 (50-69% involvement), 5 (70-89% involvement), and 6 (90-100% involvement). Darkness and homogeneity were graded as 0 (absent), 1 (slight), 2 (mild), 3 (marked), and 4 (severe)., Measurements were done at baseline and during subsequent follow-ups at 4 weeks and 12 weeks.
Sponsor Collaborator
China Medical University Hospital
Funded By
OTHER
Location
China Medical University Hospital, Taichung City, 404332, Taiwan
Other Id
CMUH108-REC1-145
Start Date
2019-11-28
Primary Completion Date
2020-09-11
Completion Date
2020-11-11
First Posted
2023-08-01
Results First Posted
Last Update Posted
2023-08-07
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05969587
Title Cn
Title En
Cysteamine Compared to Hydroquinone in Melasma
Bilingual Status
semi_complete