Clinical TrialID 8227
Folinic Acid for Prevention of Pemetrexed-induced Toxicity
NCT06010277
NSCLC|Mesothelioma|Thymoma
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Trial: 1Ingredient: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 8227
- Evidence Id
- 8227
- Core Evidence Id
- 8227
- Source Clinical Trial Id
- 8225
- Herb2 Clinical Trial Id
- HBCT008225
- Nct Id
- NCT06010277
- Title
- Folinic Acid for Prevention of Pemetrexed-induced Toxicity
- Status
- Recruiting
- Phase
- Phase 4
- Study Result
- No
- Study Condition
- NSCLC|Mesothelioma|Thymoma
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
- Intervention
- DRUG: Folinic acid
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Intervention Purpose
- Prevention
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 50
- Outcome Measure
- Difference in neutrophil count (*109/L) at day 8-10 after pemetrexed administration during 2 cycles of chemotherapy, To evaluate the haematological toxicity (continuous measure) in patients who use pemetrexed with and without rescue therapy with folinic acid., Between day 8-10 in the first 2 cycles (each cycle is 21 days)
- Sponsor Collaborator
- Amphia Hospital|Albert Schweitzer Hospital
- Funded By
- OTHER
- Location
- Amphia Hospital, Breda, Noord Brabant, 4817, Netherlands|Albert Schweitzer Hospital, Dordrecht, Zuid Holland, 3318, Netherlands
- Other Id
- 1891
- Start Date
- 2023-02-06
- Primary Completion Date
- 2024-01
- Completion Date
- 2024-01
- First Posted
- 2023-08-24
- Results First Posted
- Last Update Posted
- 2023-08-24
- Study Document
- Study Protocol and Statistical Analysis Plan, https://cdn.clinicaltrials.gov/large-docs/77/NCT06010277/Prot_SAP_000.pdf
- Study Url
- https://clinicaltrials.gov/study/NCT06010277
- Title Cn
- Title En
- Folinic Acid for Prevention of Pemetrexed-induced Toxicity
- Bilingual Status
- semi_complete