Clinical TrialID 8205

A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC

NCT05844150

SCLC

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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
8205
Evidence Id
8205
Core Evidence Id
8205
Source Clinical Trial Id
8203
Herb2 Clinical Trial Id
HBCT008203
Nct Id
NCT05844150
Title
A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC
Status
Recruiting
Phase
Phase 2|Phase 3
Study Result
No
Study Condition
SCLC
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Intervention
DRUG: PM8002|DRUG: Platinum|DRUG: Atezolizumab|DRUG: Etoposide
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Double
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
445
Outcome Measure
Objective response rate (Part 1), Objective response rate (ORR) is the proportion of subjects with complete response (CR) or partial response (PR), based on RECIST v1.1., Up to approximately 2 years|Overall survival (Part 2), Overall survival (OS) is the time from the date of randomization or first dosing date to death due to any cause., Up to approximately 2 years
Sponsor Collaborator
Biotheus Inc.
Funded By
INDUSTRY
Location
Jilin Cancer Hospital, Changchun, China
Other Id
PM8002-BC011C-SCLC-R
Start Date
2023-06-01
Primary Completion Date
2025-06
Completion Date
2025-12
First Posted
2023-05-06
Results First Posted
Last Update Posted
2024-09-05
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05844150
Title Cn
Title En
A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC
Bilingual Status
semi_complete