Clinical TrialID 8197
Intubation Conditions After RSI Using Rocuronium With Ephedrine Pretreatment
NCT05725031
Rapid Sequence Induction and Intubation
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 8197
- Evidence Id
- 8197
- Core Evidence Id
- 8197
- Source Clinical Trial Id
- 8195
- Herb2 Clinical Trial Id
- HBCT008195
- Nct Id
- NCT05725031
- Title
- Intubation Conditions After RSI Using Rocuronium With Ephedrine Pretreatment
- Status
- Recruiting
- Phase
- Phase 3
- Study Result
- No
- Study Condition
- Rapid Sequence Induction and Intubation
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
- Intervention
- DRUG: Ephedrine|DRUG: Rocuronium 0.6|DRUG: Rocuronium 0.8|DRUG: Rocuronium 1.2
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Single
- Intervention Purpose
- Health_Services_Research
- Gender
- All
- Age
- Adult
- Enrollment
- 90
- Outcome Measure
- Intubation conditions, Evaluation of intubation conditions after rapid sequence induction using rocuronium 0.6 or 0.8 mg/kg with ephedrine pretreatment, compared with 1.2 mg/kg, according to the criteria of the Good Clinical Research Practice (GCRP) in pharmacodynamic studies of NMBAs (Fuchs-Buder et al., 2007), which assess each of the following variables for their qualities described as: (excellent, good, poor) * ease of laryngoscopy (easy, fair, difficult) * vocal cords position (abducted, intermediate, closed) * reaction to tracheal tube insertion and cuff inflation (coughing: none, slight, vigorous) The 3 variables will be combined to describe intubation conditions as: * Excellent: if all qualities are excellent * Good: if all qualities are either excellent or good * Poor: if there is a single poor quality, after 60 seconds of rocuronium administration
- Sponsor Collaborator
- Ain Shams University
- Funded By
- OTHER
- Location
- Ain Shams University Hospitals, Cairo, Egypt
- Other Id
- Eph-Roc
- Start Date
- 2023-02-22
- Primary Completion Date
- 2023-07
- Completion Date
- 2023-09
- First Posted
- 2023-02-13
- Results First Posted
- Last Update Posted
- 2023-08-01
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT05725031
- Title Cn
- Title En
- Intubation Conditions After RSI Using Rocuronium With Ephedrine Pretreatment
- Bilingual Status
- semi_complete