Clinical TrialID 8185
The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry Eye
NCT06043908
Dry Eye
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 8185
- Evidence Id
- 8185
- Core Evidence Id
- 8185
- Source Clinical Trial Id
- 8183
- Herb2 Clinical Trial Id
- HBCT008183
- Nct Id
- NCT06043908
- Title
- The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry Eye
- Status
- Recruiting
- Phase
- Phase 4
- Study Result
- No
- Study Condition
- Dry Eye
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
- Intervention
- DRUG: artificial tear eyedrops|DRUG: 0.05% cyclosporine eyedrops
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult
- Enrollment
- 60
- Outcome Measure
- ocular surface disease index (OSDI), OSDI is one of the most frequently used questionnaires for evaluation of dry eye disease (DED). This includes 12 questions which measure the frequency of symptoms over the recent week, and the scores range from 0 to 100., from baseline to 3 months after treatment|Tear break-up time (TBUT)(s), BUT is the time from normal blinking to the first appearance of a break in the tear film., from baseline to 3 months after treatment|Corneal fluorescein staining (CFS), The degree of fluorescein staining of the cornea was evaluated using the National Eye Institute (NEI) scale of five corneal regions (central, superior, temporal, nasal, and inferior). The scores range from 0 to 15., from baseline to 3 months after treatment|Schirmer I test (SIt) (mm/5 minutes), The Schirmer I test is performed using sterile strips without anesthesia. The strips are placed in the lateral part of the inferior fornix of the eye for 5min and the extent of tear flow down was measured in millimeters., from baseline to 3 months after treatment|Lissamine green staining, To grade the temporal zone, the subject looks nasally; to grade the nasal zone the subject looks temporally. The upper and lower conjunctiva can also be graded., from baseline to 3 months after treatment
- Sponsor Collaborator
- Peking University Third Hospital
- Funded By
- OTHER
- Location
- Hong Qi, Beijing, Beijing, 100191, China
- Other Id
- RS01
- Start Date
- 2022-08-31
- Primary Completion Date
- 2023-12-31
- Completion Date
- 2023-12-31
- First Posted
- 2023-09-21
- Results First Posted
- Last Update Posted
- 2023-09-21
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT06043908
- Title Cn
- Title En
- The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry Eye
- Bilingual Status
- semi_complete