Clinical TrialID 8182
Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery
NCT05691764
Myocardial Injury|Cardiac Surgery
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Trial: 1Ingredient: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 8182
- Evidence Id
- 8182
- Core Evidence Id
- 8182
- Source Clinical Trial Id
- 8180
- Herb2 Clinical Trial Id
- HBCT008180
- Nct Id
- NCT05691764
- Title
- Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery
- Status
- Completed
- Phase
- Study Result
- No
- Study Condition
- Myocardial Injury|Cardiac Surgery
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
- Intervention
- DRUG: Cyclosporin|PROCEDURE: remote ischemic preconditioning|DRUG: Placebo
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Triple
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Child
- Enrollment
- 40
- Outcome Measure
- Malondialdehyde (MDA), ROS level is determined by measuring MDA concentration (nmol/mL), 1 year|Calcium cytosol concentration, Calcium concentration (nmol/mL) in cytosol is determined by ratiometric analysis on Fura Red- dyed heart cells., 1 year|Mitochondrial edema, Mitochondrial edema (%) is measured by decreasing of optical density that indicates change in mitochondrial matrix volume., 1 year
- Sponsor Collaborator
- Indonesia University
- Funded By
- OTHER
- Location
- Indonesia University, Jakarta, DKI Jakarta, 10430, Indonesia
- Other Id
- IndonesiaUAnes055
- Start Date
- 2020-09-01
- Primary Completion Date
- 2021-12-01
- Completion Date
- 2022-09-01
- First Posted
- 2023-01-20
- Results First Posted
- Last Update Posted
- 2023-01-20
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT05691764
- Title Cn
- Title En
- Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery
- Bilingual Status
- semi_complete