Clinical TrialID 8100

Chlorpheniramine Nasal Spray to Accelerate COVID-19 Clinical Recovery in an Outpatient Setting: ACCROS-III

NCT05886829

COVID-19|Symptoms and Signs|COVID-19 Pandemic|Coronavirus Disease 2019|Coronavirus Infections

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Record Fields

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Clinical Trial Id
8100
Evidence Id
8100
Core Evidence Id
8100
Source Clinical Trial Id
8099
Herb2 Clinical Trial Id
HBCT008099
Nct Id
NCT05886829
Title
Chlorpheniramine Nasal Spray to Accelerate COVID-19 Clinical Recovery in an Outpatient Setting: ACCROS-III
Status
Completed
Phase
Phase 2|Phase 3
Study Result
No
Study Condition
COVID-19|Symptoms and Signs|COVID-19 Pandemic|Coronavirus Disease 2019|Coronavirus Infections
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Intervention
COMBINATION_PRODUCT: Chlorpheniramine Maleate 0.4% Nasal Spray|COMBINATION_PRODUCT: Placebo
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Double
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
157
Outcome Measure
Daily symptoms score (DSS), Change from baseline daily symptoms score (DSS) to day 7 The DSS is an instrument comprised of a four-point severity rating scale ranging from 0 to 3. 0 = no symptoms 1. = mild symptoms 2. = moderate symptoms 3. = severe symptoms., Baseline through day 7|Visual Analog Scale (VAS), Change from baseline visual analog scale (VAS) to day 7 The VAS is a quantitative method that evaluates the severity of symptoms on a scale of 1-10 (no signs to worst symptoms). A 10 cm line is used to grade the severity of symptoms from "no symptoms" (0 cm) to "the highest level of symptoms" (10 cm)., Baseline through day 7
Sponsor Collaborator
Dr. Ferrer BioPharma|Hospital CEMESA Cortés, San Pedro Sula, Honduras
Funded By
INDUSTRY
Location
Hospital CEMESA, Cortés, San Pedro Sula, Honduras
Other Id
DFB-006
Start Date
2022-07-27
Primary Completion Date
2023-01-19
Completion Date
2023-02-01
First Posted
2023-06-02
Results First Posted
Last Update Posted
2023-06-02
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05886829
Title Cn
Title En
Chlorpheniramine Nasal Spray to Accelerate COVID-19 Clinical Recovery in an Outpatient Setting: ACCROS-III
Bilingual Status
semi_complete