Clinical TrialID 808

Loperamide Grapefruit Juice Interaction PK Trial

NCT00806299

Drug Interaction

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Trial: 1Herb: 1Links: 1
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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
808
Evidence Id
808
Core Evidence Id
808
Source Clinical Trial Id
791
Herb2 Clinical Trial Id
HBCT000791
Nct Id
NCT00806299
Title
Loperamide Grapefruit Juice Interaction PK Trial
Status
Completed
Phase
Phase 1
Study Result
No
Study Condition
Drug Interaction
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Intervention
DRUG: Loperamide / Red Grapefruit Juice|DRUG: Loperamide/ White Grapefruit Juice|DRUG: Loperamide / Pink Grapefruit Juice
Intervention Allocation
Randomized
Intervention Model
Crossover
Intervention Mask
Intervention Purpose
Basic_Science
Gender
All
Age
Adult
Enrollment
33
Outcome Measure
Pharmacokinetic parameters, Blood samples will be collected before dosing (predose) and at 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 10, 14, 24, 30, 36, and 46 hours following each of the three doses
Sponsor Collaborator
Johnson & Johnson Consumer and Personal Products Worldwide
Funded By
INDUSTRY
Location
Cetero Research, Fargo, North Dakota, 58104, United States
Other Id
LOPDIR1007
Start Date
2008-11
Primary Completion Date
2008-11
Completion Date
2008-11
First Posted
2008-12-10
Results First Posted
Last Update Posted
2011-10-06
Study Document
Study Url
https://clinicaltrials.gov/study/NCT00806299
Title Cn
Title En
Loperamide Grapefruit Juice Interaction PK Trial
Bilingual Status
semi_complete