Clinical TrialID 8043
Long-term Metabolic Effects of Cafestol
NCT05672433
Obesity, Abdominal
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 8043
- Evidence Id
- 8043
- Core Evidence Id
- 8043
- Source Clinical Trial Id
- 8039
- Herb2 Clinical Trial Id
- HBCT008039
- Nct Id
- NCT05672433
- Title
- Long-term Metabolic Effects of Cafestol
- Status
- Phase
- Study Result
- No
- Study Condition
- Obesity, Abdominal
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
- Intervention
- DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Cafestol
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Quadruple
- Intervention Purpose
- Prevention
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 40
- Outcome Measure
- Steady state plasma glucose during stage 2 of insulin suppression test (mmol/L), Subjects are administered a 25 μg octreotide bolus at time-point 0 minutes and subsequently infused with 0.27 μg octreotide / m2 • minute, 6 milliunits (mU) insulin / m2 • minute, and 50 mg glucose / m2 • minute. At time-point 120 minutes, infusion speeds were increased to to 32 mU insulin / m2 • minute and 267 mg glucose / m2 • minute., 220, 230 and 240 minutes after test-start. Comparison between pre-intervention and end-intervention steady state plasma glucose.|Steady state plasma glucose during stage 1 of insulin suppression test (mmol/L), Subjects are administered a 25 μg octreotide bolus at time-point 0 minutes and subsequently infused with 0.27 μg octreotide / m2 • minute, 6 mU insulin / m2 • minute, and 50 mg glucose / m2 • min., 100, 110 and 120 minutes after test-start. Comparison between pre-intervention and end-intervention steady state plasma glucose.|Area under the curve for glucose during mixed meal test (mmol/L*min), Area under the curve for glucose during a mixed meal test., -15 to 240 minutes from ingestion of standardized meal at time point 0 minutes. Comparison between pre-intervention and end-intervention area under the curves.
- Sponsor Collaborator
- University of Aarhus|Aarhus University Hospital
- Funded By
- OTHER
- Location
- Steno Diabetes Center Aarhus, Aarhus, Aarhus N, 8200, Denmark
- Other Id
- cafestol.longterm
- Start Date
- 2022-06-28
- Primary Completion Date
- 2023-02-01
- Completion Date
- 2023-03-01
- First Posted
- 2023-01-05
- Results First Posted
- Last Update Posted
- 2023-01-05
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT05672433
- Title Cn
- Title En
- Long-term Metabolic Effects of Cafestol
- Bilingual Status
- semi_complete