Clinical TrialID 8021
Firefighter Thermoregulatory Responses in Active Fire With Betaine Supplementation
NCT06042270
Body Temperature Changes|Body Water Dehydration|Inflammation
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Trial: 1Ingredient: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 8021
- Evidence Id
- 8021
- Core Evidence Id
- 8021
- Source Clinical Trial Id
- 8025
- Herb2 Clinical Trial Id
- HBCT008025
- Nct Id
- NCT06042270
- Title
- Firefighter Thermoregulatory Responses in Active Fire With Betaine Supplementation
- Status
- Active_Not_Recruiting
- Phase
- Study Result
- No
- Study Condition
- Body Temperature Changes|Body Water Dehydration|Inflammation
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
- Intervention
- DIETARY_SUPPLEMENT: Betaine|DIETARY_SUPPLEMENT: Placebo
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Quadruple
- Intervention Purpose
- Prevention
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 17
- Outcome Measure
- Thermoregulation, Core temperature (Degrees C), skin temperature (Degrees C), 10 minutes before the live burn, during the ~15 minute live burn, 10, 20, and 30 minutes after the live burn.|Stress (enzyme linked immunoassays), Salivary expression of Testosterone, Cortisol, interleukin-8, and interleukin 6 will be measured., before, immediately after, 10 minutes, and 20 minutes after live burn|Stress (respiration efficiency), Air tank pounds per square inch (PSI) will be recorded, immediately before and immediately after the completion of the live burn|Sweat Rate, Changes in body weight in kg will be used to find loss of sweat in L, immediately before and immediately after the completion of the live burn|Sweat Content, Tegaderm patches will be worn during the live burn to analyze sodium concentration in sweat., immediately before and immediately after the completion of the live burn|Subjective measures, Visual analog scales will be given to participants for subjective thermal sensation, rate of perceived exertion, and thirst, immediately before and immediately after the completion of the live burn
- Sponsor Collaborator
- Michael J. Ormsbee
- Funded By
- OTHER
- Location
- Institute of Sports Science and Medicine, Tallahassee, Florida, 32301, United States
- Other Id
- STUDY00004218
- Start Date
- 2023-12-20
- Primary Completion Date
- 2024-03-01
- Completion Date
- 2024-09
- First Posted
- 2023-09-18
- Results First Posted
- Last Update Posted
- 2024-04-04
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT06042270
- Title Cn
- Title En
- Firefighter Thermoregulatory Responses in Active Fire With Betaine Supplementation
- Bilingual Status
- semi_complete