Clinical TrialID 791

Consumption of Apple Juice in Hemodialysis Patients

NCT02974491

Oxidative Stress

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Record Fields

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Clinical Trial Id
791
Evidence Id
791
Core Evidence Id
791
Source Clinical Trial Id
775
Herb2 Clinical Trial Id
HBCT000775
Nct Id
NCT02974491
Title
Consumption of Apple Juice in Hemodialysis Patients
Status
Completed
Phase
Study Result
No
Study Condition
Oxidative Stress
Study Type
Interventional
Study Design
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Intervention
OTHER: Fuji apple juice
Intervention Allocation
Intervention Model
Single_Group
Intervention Mask
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
6
Outcome Measure
Measuring oxidative stress biomarkers, Total antioxidant status (TAS) (mmol/L) and total oxidant status (TOS) (mmol/L) was measured at the baseline period, after 30 and 60 min of acute consumption of 300 and 150 mL of Fuji apple (Malus domestica Borkh) juice. Patients were not fasted for the withdrawal of blood. This measure was taken to prevent discomfort among volunteers. Venous blood samples were collected through aseptic venipuncture on the opposite arm of the arteriovenous fistula by a qualified professional using a vacuum system into heparin or EDTA-containing tubes or tubes without additives according to established standards of clinical and biological safety., Change from baseline at 30 and 60 minutes|Measuring endogenous antioxidant enzymes, Catalase (U mg/Hb), glutathione peroxidase (U mg/Hb) and superoxide dismutase (U mg/Hb) was measured at the baseline period, after 30 and 60 min of acute consumption of 300 and 150 mL of Fuji apple (Malus domestica Borkh) juice. Patients were not fasted for the withdrawal of blood. This measure was taken to prevent discomfort among volunteers. Venous blood samples were collected through aseptic venipuncture on the opposite arm of the arteriovenous fistula by a qualified professional using a vacuum system into heparin or EDTA-containing tubes or tubes without additives according to established standards of clinical and biological safety., Change from baseline at 30 and 60 minutes|Measuring oxidative stress biomarkers, Ascorbic acid (micromole/L) was measured at the baseline period, after 30 and 60 min of acute consumption of 300 and 150 mL of Fuji apple (Malus domestica Borkh) juice. Patients were not fasted for the withdrawal of blood. This measure was taken to prevent discomfort among volunteers. Venous blood samples were collected through aseptic venipuncture on the opposite arm of the arteriovenous fistula by a qualified professional using a vacuum system into heparin or EDTA-containing tubes or tubes without additives according to established standards of clinical and biological safety., Change from baseline at 30 and 60 minutes|Measuring oxidative stress biomarkers, Reduced glutathione (micromole mg/Hb) was measured at the baseline period, after 30 and 60 min of acute consumption of 300 and 150 mL of Fuji apple (Malus domestica Borkh) juice. Patients were not fasted for the withdrawal of blood. This measure was taken to prevent discomfort among volunteers. Venous blood samples were collected through aseptic venipuncture on the opposite arm of the arteriovenous fistula by a qualified professional using a vacuum system into heparin or EDTA-containing tubes or tubes without additives according to established standards of clinical and biological safety., Change from baseline at 30 and 60 minutes|Measuring serum biochemical parameters, Potassium (mmol/L), phosphorus (mmol/L) and glucose (mmol/L) was measured at the baseline period, after 30 and 60 min of acute consumption of 300 and 150 mL of Fuji apple (Malus domestica Borkh) juice. Patients were not fasted for the withdrawal of blood. This measure was taken to prevent discomfort among volunteers. Venous blood samples were collected through aseptic venipuncture on the opposite arm of the arteriovenous fistula by a qualified professional using a vacuum system into heparin or EDTA-containing tubes or tubes without additives according to established standards of clinical and biological safety., Change from baseline at 30 and 60 minutes|Measuring serum biochemical parameters, Uric acid (micromole/L) was measured at the baseline period, after 30 and 60 min of acute consumption of 300 and 150 mL of Fuji apple (Malus domestica Borkh) juice. Patients were not fasted for the withdrawal of blood. This measure was taken to prevent discomfort among volunteers. Venous blood samples were collected through aseptic venipuncture on the opposite arm of the arteriovenous fistula by a qualified professional using a vacuum system into heparin or EDTA-containing tubes or tubes without additives according to established standards of clinical and biological safety., Change from baseline at 30 and 60 minutes|Evaluating heigth, Height (meters) data were obtained from the patient's files., at baseline|Evaluating weight, Weight (kilograms) data were obtained from the patient's files., At baseline|Evaluating body mass index, Body mass index (BMI) (Kg/m2) data were obtained from the patient's files., At baseline|Evaluating medication, Medication data were obtained from the patient's files., At baseline|Evaluating adequacy of the dialysis treatment, Adequacy of the dialysis treatment was captured by extracting the routine Kt/V from the medical record., At baseline
Sponsor Collaborator
Universidade Federal de Santa Catarina
Funded By
OTHER
Location
Other Id
37090614.6.0000.0118
Start Date
2015-08
Primary Completion Date
2015-10
Completion Date
2015-10
First Posted
2016-11-28
Results First Posted
Last Update Posted
2016-11-28
Study Document
Study Url
https://clinicaltrials.gov/study/NCT02974491
Title Cn
Title En
Consumption of Apple Juice in Hemodialysis Patients
Bilingual Status
semi_complete