Clinical TrialID 7838
Nasal Irrigation With Combination of 0.9% NaCl and Binahong Extract (Anredera Cordifolia) 2,5% In Allergic Rhinitis
NCT05960526
Allergic Rhinitis|Allergic Rhinitis Due to House Dust Mite
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 7838
- Evidence Id
- 7838
- Core Evidence Id
- 7838
- Source Clinical Trial Id
- 7835
- Herb2 Clinical Trial Id
- HBCT007835
- Nct Id
- NCT05960526
- Title
- Nasal Irrigation With Combination of 0.9% NaCl and Binahong Extract (Anredera Cordifolia) 2,5% In Allergic Rhinitis
- Status
- Enrolling_By_Invitation
- Phase
- Phase 1
- Study Result
- No
- Study Condition
- Allergic Rhinitis|Allergic Rhinitis Due to House Dust Mite
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
- Intervention
- DRUG: extract Binahong|DRUG: Isotonic saline nasal irrigation
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Single
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 80
- Outcome Measure
- mRNA expression (IL-4, Il-6, IL-13, and TNF-α), RNA samples were obtained from the epithelial mucosa of the nasal mucosa using a cytology brush by inserting the brush and rubbing it on the superior and medial inferior concha mucosa 2-3 times in a circular and parallel motion on both the right and left nasal cavities., Change from baseline mRNA at two weeks.
- Sponsor Collaborator
- Gadjah Mada University
- Funded By
- OTHER
- Location
- RS PKU Muhammadiyah, Yogyakarta, DIY, 55294, Indonesia
- Other Id
- KE/FK/0419/EC/2023
- Start Date
- 2023-05-06
- Primary Completion Date
- 2024-09-06
- Completion Date
- 2024-12-10
- First Posted
- 2023-07-25
- Results First Posted
- Last Update Posted
- 2024-02-28
- Study Document
- Study Protocol and Informed Consent Form, https://cdn.clinicaltrials.gov/large-docs/26/NCT05960526/Prot_ICF_000.pdf
- Study Url
- https://clinicaltrials.gov/study/NCT05960526
- Title Cn
- Title En
- Nasal Irrigation With Combination of 0.9% NaCl and Binahong Extract (Anredera Cordifolia) 2,5% In Allergic Rhinitis
- Bilingual Status
- semi_complete