Clinical TrialID 7824
Combination of Curcuminoid With Acupressure for Inflammation and Pain in the Elderly With Osteoarthritis Genu
NCT06105840
Osteoarthritis, Knee
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 7824
- Evidence Id
- 7824
- Core Evidence Id
- 7824
- Source Clinical Trial Id
- 7821
- Herb2 Clinical Trial Id
- HBCT007821
- Nct Id
- NCT06105840
- Title
- Combination of Curcuminoid With Acupressure for Inflammation and Pain in the Elderly With Osteoarthritis Genu
- Status
- Enrolling_By_Invitation
- Phase
- Phase 1|Phase 2
- Study Result
- No
- Study Condition
- Osteoarthritis, Knee
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
- Intervention
- PROCEDURE: Acupressure and Standardized Curcuminoid from Turmeric Extract|PROCEDURE: Sham Acupressure and Placebo
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Triple
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 70
- Outcome Measure
- Inflammation Marker, Inflammation markers are carried out by measuring Leukocyte Number, NLR, Blood Sediment Rate and COX-2 hormone. Outcome measurements will be carried out a complete blood test using a Hematology Analyzer. Leukocyte numbers measured in microliter (mcL). Neutrophil-Lymphocyte Count Ratio can be calculated from the number of neutrophils (cells) and lymphocytes (cells). Neutrophils and lymphocytes will be combined to report Neutrophil-Lymphocyte Count Ratio in %. Blood Sediment Rate is a measurement of the difference in the decrease in height of red blood cells in a test tube (mm) divided by the time (hours) required for all of them to settle to the bottom of the test tube. There will be combined to report Blood Sediment Rate in mm/hr. The COX-2 hormone examination was carried out using the Enzyme Linked Immunosorbent Assay (ELISA). The amount of COX-2 Hormone in the blood in nanograms and blood sample volume in milliliters will be combined to report secretion of COX-2 in ng/mL, Outcome measurements will be carried out before starting therapy and after 3 weeks of therapy|Endorphin Hormones, Secretion of endorphin hormones Endorphins, in this case beta endorphin, are hormones released by the pituitary gland in response to stress or pain, which are also secreted in blood plasma. Endorphin hormone examination is carried out using the Enzyme Linked Immunosorbent Assay (ELISA) method on blood plasma. The amount of Endorphin Hormone in the blood in nanograms and the blood sample volume in milliliters will be combined to report secretion of COX-2 in ng/mL, Outcome measurements will be carried out before starting therapy and after 3 weeks of therapy
- Sponsor Collaborator
- Gadjah Mada University
- Funded By
- OTHER
- Location
- Padukuhan Tanjungsari Kelurahan Sukoharjo Ngaglik, Sleman, Yogyakarta, Indonesia
- Other Id
- KE/FK/0674/EC/2023
- Start Date
- 2023-08-27
- Primary Completion Date
- 2023-10-31
- Completion Date
- 2023-10-31
- First Posted
- 2023-10-30
- Results First Posted
- Last Update Posted
- 2023-10-30
- Study Document
- Study Protocol, Statistical Analysis Plan, and Informed Consent Form, https://cdn.clinicaltrials.gov/large-docs/40/NCT06105840/Prot_SAP_ICF_000.pdf
- Study Url
- https://clinicaltrials.gov/study/NCT06105840
- Title Cn
- Title En
- Combination of Curcuminoid With Acupressure for Inflammation and Pain in the Elderly With Osteoarthritis Genu
- Bilingual Status
- semi_complete