Clinical TrialID 761
Cardio-vascular Protective Effects of Wolfberry in Middle-aged and Older Adults
NCT03535844
Cardiovascular Diseases|Aging
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 761
- Evidence Id
- 761
- Core Evidence Id
- 761
- Source Clinical Trial Id
- 744
- Herb2 Clinical Trial Id
- HBCT000744
- Nct Id
- NCT03535844
- Title
- Cardio-vascular Protective Effects of Wolfberry in Middle-aged and Older Adults
- Status
- Completed
- Phase
- Study Result
- Yes
- Study Condition
- Cardiovascular Diseases|Aging
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
- Intervention
- OTHER: Wolfberry|OTHER: Healthy diet
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Double
- Intervention Purpose
- Prevention
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 41
- Outcome Measure
- Change in Lipidomic Profiles, The main classes of lipids in the cell membrane, Pre- and post-intervention (Week 16)|Change in Carotid Intima Media Thickness, Carotid intima media thickness measured using high-frequency ultrasonographic imaging, Pre- and post-intervention (Week 16)|Change in Endothelial Progenitor Cells, Quantity and quality of circulating endothelial progenitor cells, Pre- and post-intervention (Week 16)|Change in Flow Mediated Dilation, Brachial artery flow mediated dilation measured using high-frequency ultrasonographic imaging, Pre- and post-intervention (Week 16)|Change in Plasma Nitric Oxide, Concentrations of plasma total nitrate/nitrite using commercially available ELISA assay kits., Pre- and post-intervention (Week 16)|Change in Blood Carotenoid Status, Fasting state plasma carotenoids using high performance liquid chromatography., Pre- and post-intervention (Week 16)|Change in Plasma Endothelin-1, Concentrations of plasma endothelin-1 using commercially available ELISA assay kits., Pre- and post-intervention (Week 16)|Change in Plasma ICAM-1, Concentrations of plasma intercellular adhesion molecule-1 using commercially available ELISA assay kits., Pre- and post-intervention (Week 16)
- Sponsor Collaborator
- National University of Singapore|National University Hospital, Singapore|Ministry of Education, Singapore
- Funded By
- OTHER
- Location
- National University of Singapaore, Singapore, 117546, Singapore|National University Hospital, Singapore, 119074, Singapore
- Other Id
- S2
- Start Date
- 2018-08-06
- Primary Completion Date
- 2019-09-26
- Completion Date
- 2019-09-26
- First Posted
- 2018-05-24
- Results First Posted
- 2020-04-01
- Last Update Posted
- 2020-04-22
- Study Document
- Study Protocol and Statistical Analysis Plan, https://cdn.clinicaltrials.gov/large-docs/44/NCT03535844/Prot_SAP_000.pdf|Informed Consent Form, https://cdn.clinicaltrials.gov/large-docs/44/NCT03535844/ICF_001.pdf
- Study Url
- https://clinicaltrials.gov/study/NCT03535844
- Title Cn
- Title En
- Cardio-vascular Protective Effects of Wolfberry in Middle-aged and Older Adults
- Bilingual Status
- semi_complete