Clinical TrialID 7571

Study to Verify the Effectiveness and Safety of Isothymol or Carvacrol Compound Against SARS-CoV-2 in COVID-19 Patients

NCT05445089

COVID-19|COVID-19 Pneumonia|COVID-19 Respiratory Infection|COVID-19 Acute Respiratory Distress Syndrome|COVID-19 Lower Respiratory Infection

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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
7571
Evidence Id
7571
Core Evidence Id
7571
Source Clinical Trial Id
7567
Herb2 Clinical Trial Id
HBCT007567
Nct Id
NCT05445089
Title
Study to Verify the Effectiveness and Safety of Isothymol or Carvacrol Compound Against SARS-CoV-2 in COVID-19 Patients
Status
Completed
Phase
Phase 2|Phase 3
Study Result
No
Study Condition
COVID-19|COVID-19 Pneumonia|COVID-19 Respiratory Infection|COVID-19 Acute Respiratory Distress Syndrome|COVID-19 Lower Respiratory Infection
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Intervention
DRUG: Carvacrol|OTHER: Control group
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Single
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
600
Outcome Measure
Mortality Rate Among COVID-19 Patients, The incidence of mortality in the first 15 days., Day 1 to Day 15|Quantitative Evaluation of Inflammatory Mediator Interleukin 6 (IL-6) by test ELISA as Collected Over Time to Day 15, Interleukin 6 (IL-6) in pg/ml, Day 1 to Day 15|Quantitative Evaluation of Immunoglobulin M (IgM) by test ELISA as Collected Over Time to Day 15, IgM in mg/dl, Day 1 to Day 15|Quantitative Evaluation of Immunoglobulin G (IgG) by test ELISA as Collected Over Time to Day 15, IgG in mg/dl, Day 1 to Day 15|Proportion of Patients with COVID-19 who Require Intensive Care Unit (ICU)-Level Care, Mechanical Ventilatory Support (MV), and/or Extracorporeal Membrane Oxygenation (ECMO) Over Time to Day 15, As a measure of disease acuity and severity., Day 1 to Day 15|Requirement for Extracorporeal Membrane Oxygenation (ECMO) in COVID-19 Patients Over Time to Day 15, A measure of disease morbidity., Day 1 to Day 15
Sponsor Collaborator
Instituto Venezolano de Investigaciones Cientificas
Funded By
OTHER
Location
Hospital Dr. Leopoldo Manrique Terrero - Periférico de Coche., Caracas, Miranda, 1090, Venezuela
Other Id
LAB-2020-01|ISRCTN registry
Start Date
2020-08-01
Primary Completion Date
2020-11-01
Completion Date
2020-12-15
First Posted
2022-07-06
Results First Posted
Last Update Posted
2022-07-08
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05445089
Title Cn
Title En
Study to Verify the Effectiveness and Safety of Isothymol or Carvacrol Compound Against SARS-CoV-2 in COVID-19 Patients
Bilingual Status
semi_complete