Clinical TrialID 7530

Assessment of Reward Responses to Erythritol Using Flavor Preference Learning

NCT05279183

Reward Responses|Gastrointestinal Hormones|Glycemic Control|Appetite|Satiation|Emotional State

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Record Fields

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Clinical Trial Id
7530
Evidence Id
7530
Core Evidence Id
7530
Source Clinical Trial Id
7525
Herb2 Clinical Trial Id
HBCT007525
Nct Id
NCT05279183
Title
Assessment of Reward Responses to Erythritol Using Flavor Preference Learning
Status
Completed
Phase
Study Result
No
Study Condition
Reward Responses|Gastrointestinal Hormones|Glycemic Control|Appetite|Satiation|Emotional State
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Intervention
DIETARY_SUPPLEMENT: Erythritol|DIETARY_SUPPLEMENT: Sucrose|DIETARY_SUPPLEMENT: Sucralose
Intervention Allocation
Randomized
Intervention Model
Crossover
Intervention Mask
Quadruple
Intervention Purpose
Basic_Science
Gender
All
Age
Adult
Enrollment
20
Outcome Measure
Assessment of the change of explicit wanting (reward response) to oral erythritol versus sucrose and sucralose as change from baseline to post-test visit., Beverages are consumed during the screening visit, conditioning visits and the post-test visit. The beverages will be consumed at t = 0min, t = 45min and t = 90min and afterwards explicit wanting will be assessed. Explicit wanting of the consumed beverages is assessed by Visual Analogue Scale (VAS) as "How much do you want to drink of the drink". The Visual Analogue Scale consists of a horizontal, unstructured, 10 cm line representing the minimum (0.0 points) labeled with "not much at all" to the maximum rating (10.0 points) labeled with "very much". Participants are instructed to draw a dash in the answer line to indicate the magnitude of their subjective sensation at the present time point., from baseline to post-test visit (at t = 0min, t = 45min and t = 90min)
Sponsor Collaborator
University Hospital, Basel, Switzerland
Funded By
OTHER
Location
St. Claraspital, Basel, 4002, Switzerland
Other Id
PolyReward
Start Date
2022-03-17
Primary Completion Date
2022-09-16
Completion Date
2022-09-16
First Posted
2022-03-15
Results First Posted
Last Update Posted
2022-10-12
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05279183
Title Cn
Title En
Assessment of Reward Responses to Erythritol Using Flavor Preference Learning
Bilingual Status
semi_complete