Clinical TrialID 753

Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash

NCT04723732

Gingivitis|Dental Plaque

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Record Fields

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Clinical Trial Id
753
Evidence Id
753
Core Evidence Id
753
Source Clinical Trial Id
737
Herb2 Clinical Trial Id
HBCT000737
Nct Id
NCT04723732
Title
Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash
Status
Completed
Phase
Study Result
No
Study Condition
Gingivitis|Dental Plaque
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Intervention
DRUG: Myrrh mouthwash|DRUG: Chlorhexidine mouthwash|DRUG: Normal saline
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Triple
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
24
Outcome Measure
Change from Baseline in inflammation on the proinflammatory interleukin (IL)-1β biomarker at Day 14, IL-1β is an important mediator of the inflammatory response. Elevated IL-1β levels have been reported in a number of infectious disease conditions and in noninfectious inflammatory conditions. Human IL-1β ELISA kit by BioVendor was utilized to determine the IL-1β level. Preparation of reagents, execution of test protocol, and calculation of results were done adhering to the manufacturer's Product Data Sheet enclosed with the kit. The absorbance of each strip was read on a spectro-photometer at 450 nm wave length., Baseline and Day 14
Sponsor Collaborator
King Abdulaziz University
Funded By
OTHER
Location
King Abdul Aziz University, Jeddah, Makkah, 21589, Saudi Arabia
Other Id
058-15
Start Date
2017-08-15
Primary Completion Date
2018-08-15
Completion Date
2018-12-15
First Posted
2021-01-26
Results First Posted
Last Update Posted
2021-01-26
Study Document
Study Url
https://clinicaltrials.gov/study/NCT04723732
Title Cn
Title En
Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash
Bilingual Status
semi_complete