Clinical TrialID 7468

Topical SGX302 for Mild-to-Moderate Psoriasis

NCT05442190

Psoriasis|Plaque Psoriasis|Psoriasis Vulgaris

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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
7468
Evidence Id
7468
Core Evidence Id
7468
Source Clinical Trial Id
7463
Herb2 Clinical Trial Id
HBCT007463
Nct Id
NCT05442190
Title
Topical SGX302 for Mild-to-Moderate Psoriasis
Status
Recruiting
Phase
Phase 2
Study Result
No
Study Condition
Psoriasis|Plaque Psoriasis|Psoriasis Vulgaris
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Intervention
DRUG: Hypericin|DRUG: Placebo
Intervention Allocation
Randomized
Intervention Model
Sequential
Intervention Mask
Quadruple
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
42
Outcome Measure
Number of patients that achieve a 0 or 1 score using the 5-point Investigator's Global Assessment scale, The percentage of patients in each treatment group that achieve a 0 or 1 score (Clear or Almost Clear) evaluation using the 5-point Investigator's Global Assessment (IGA) scale. The 5-point IGA scale: * Score 0: Clear - No signs of psoriasis; post-inflammatory hyperpigmentation may be present * Score 1: Almost Clear - No thickening; normal to pink coloration; no to minimal focal scaling * Score 2: Mild - Just detectable to mild thickening; pink to light red coloration; predominantly fine scaling * Score 3: Moderate - Clear distinguishable to moderate thickening; dull to bright red; moderate scaling * Score 4: Severe - Severe thickening with hard edges; bright to deep red coloration; severe/coarse scaling covering almost all lesions, 18 weeks
Sponsor Collaborator
Soligenix
Funded By
INDUSTRY
Location
Therapeutics Clinical Research, San Diego, California, 92123, United States
Other Id
HPN-PSR-01
Start Date
2022-12-14
Primary Completion Date
2025-04
Completion Date
2025-06
First Posted
2022-07-01
Results First Posted
Last Update Posted
2024-04-24
Study Document
Study Url
https://clinicaltrials.gov/study/NCT05442190
Title Cn
Title En
Topical SGX302 for Mild-to-Moderate Psoriasis
Bilingual Status
semi_complete