Clinical TrialID 7370
Citrulline Supplementation On Vascular Responsiveness and Function in Postmenopausal Women
NCT05600413
Menopause
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 7370
- Evidence Id
- 7370
- Core Evidence Id
- 7370
- Source Clinical Trial Id
- 7364
- Herb2 Clinical Trial Id
- HBCT007364
- Nct Id
- NCT05600413
- Title
- Citrulline Supplementation On Vascular Responsiveness and Function in Postmenopausal Women
- Status
- Completed
- Phase
- Study Result
- No
- Study Condition
- Menopause
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
- Intervention
- DIETARY_SUPPLEMENT: L-Citrulline|DIETARY_SUPPLEMENT: Placebo
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Double
- Intervention Purpose
- Basic_Science
- Gender
- Female
- Age
- Adult, Older_Adult
- Enrollment
- 26
- Outcome Measure
- Microvascular endothelial function, Endothelial function will be assessed via reactive hyperemic index using the EndoPAT device., 4 weeks|Changes in brachial and aortic blood pressure responses via automated sphygmomanometry during metaboreflex activation, Brachial and aortic blood pressures (systolic and diastolic) will be assessed using an arm cuff during isometric handgrip exercise and postexercise muscle ischemia., 4 weeks|Changes in aortic hemodynamics using pulse wave analysis during metaboreflex activation, The speed and reflection pressures, both representing aortic hemodynamic parameters, will be assessed using radial applanation tonometry and a validated transfer function (AtCor Medical) during isometric handgrip exercise and postexercise muscle ischemia., 4 weeks|Blood flow during dynamic exercise, Blood flow will be measured using ultrasound in the superficial femoral and brachial artery during dynamic exercises superimposed with the cold pressor test., 4 weeks|Muscle oxygenation during dynamic exercise, Muscle oxygenation will be measured using near infrared spectroscopy during dynamic exercises superimposed with the cold pressor test., 4 weeks
- Sponsor Collaborator
- Texas Tech University
- Funded By
- OTHER
- Location
- Texas Tech University, Lubbock, Texas, 79409, United States
- Other Id
- IRB2019-1197
- Start Date
- 2020-07-07
- Primary Completion Date
- 2022-04-27
- Completion Date
- 2022-04-27
- First Posted
- 2022-10-31
- Results First Posted
- Last Update Posted
- 2022-10-31
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT05600413
- Title Cn
- Title En
- Citrulline Supplementation On Vascular Responsiveness and Function in Postmenopausal Women
- Bilingual Status
- semi_complete