Clinical TrialID 7279
Enoxolone in Major Depression - Biomarker-outcome Relationship
NCT05570110
Unipolar Depression
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 7279
- Evidence Id
- 7279
- Core Evidence Id
- 7279
- Source Clinical Trial Id
- 7270
- Herb2 Clinical Trial Id
- HBCT007270
- Nct Id
- NCT05570110
- Title
- Enoxolone in Major Depression - Biomarker-outcome Relationship
- Status
- Recruiting
- Phase
- Phase 1|Phase 2
- Study Result
- No
- Study Condition
- Unipolar Depression
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
- Intervention
- DRUG: Enoxolone
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Quadruple
- Intervention Purpose
- Diagnostic
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 60
- Outcome Measure
- Systolic blood pressure, Systolic blood pressure at rest at baseline as a predictor for treatment differentiation, Baseline, as predictor for differentiation of treatment groups clinical response|Urine aldosterone/cortisol ratio, Ratio of nocturnal urine aldosterone concentration/urine cortisol concentration, Baseline, as predictor for differentiation of treatment groups clinical resposne|Depression rating, Hamilton depression rating scale (HAMD) - 17 items; higher is worse, change from baseline to week 4, with systolic blood pressure as covariate|Depression self rating, Patient health questionnaire for depression (PHQ-9), higher is worse, change from baseline to week 4, with systolic blood pressure as covariate
- Sponsor Collaborator
- Philipps University Marburg Medical Center|Slovak Academy of Sciences
- Funded By
- OTHER
- Location
- Clinic for Psychiatry and Psychotherapy, Marburg, Hessen, 35039, Germany
- Other Id
- MNS_02.1
- Start Date
- 2022-09-23
- Primary Completion Date
- 2025-03
- Completion Date
- 2025-03
- First Posted
- 2022-10-06
- Results First Posted
- Last Update Posted
- 2024-04-09
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT05570110
- Title Cn
- Title En
- Enoxolone in Major Depression - Biomarker-outcome Relationship
- Bilingual Status
- semi_complete