Clinical TrialID 7231
Study to Evaluate the Pressor Effect of Oral Tyramine During Ozanimod Treatment in Healthy Adult Participants
NCT04978298
Healthy Volunteers
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Trial: 1Ingredient: 1Links: 1
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 7231
- Evidence Id
- 7231
- Core Evidence Id
- 7231
- Source Clinical Trial Id
- 7221
- Herb2 Clinical Trial Id
- HBCT007221
- Nct Id
- NCT04978298
- Title
- Study to Evaluate the Pressor Effect of Oral Tyramine During Ozanimod Treatment in Healthy Adult Participants
- Status
- Completed
- Phase
- Phase 1
- Study Result
- No
- Study Condition
- Healthy Volunteers
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
- Intervention
- OTHER: Placebo|DRUG: Rasigiline|DRUG: Phenelzine|DRUG: Ozanimod
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Double
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult
- Enrollment
- 128
- Outcome Measure
- Tyramine Sensitivity Factor (TSF), The ratio of Tyramine pressor response (Tyr30) in Period 1 over Tyr30 in Period 3., Up to Day 85
- Sponsor Collaborator
- Celgene
- Funded By
- INDUSTRY
- Location
- Local Institution - 001, Anaheim, California, 92801, United States
- Other Id
- RPC-1063-CP-005
- Start Date
- 2021-07-19
- Primary Completion Date
- 2023-02-26
- Completion Date
- 2023-02-26
- First Posted
- 2021-07-27
- Results First Posted
- Last Update Posted
- 2023-08-31
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT04978298
- Title Cn
- Title En
- Study to Evaluate the Pressor Effect of Oral Tyramine During Ozanimod Treatment in Healthy Adult Participants
- Bilingual Status
- semi_complete