Clinical TrialID 71
Clinical Evaluation of the Pharmacokinetic Goldenseal-Metformin Interaction in Diabetic Patients
NCT05081583
Interaction, Adverse Herb-Drug|Diabetes Mellitus, Type 2
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Trial: 1Herb: 1Links: 1
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 71
- Evidence Id
- 71
- Core Evidence Id
- 71
- Source Clinical Trial Id
- 66
- Herb2 Clinical Trial Id
- HBCT000066
- Nct Id
- NCT05081583
- Title
- Clinical Evaluation of the Pharmacokinetic Goldenseal-Metformin Interaction in Diabetic Patients
- Status
- Active_Not_Recruiting
- Phase
- Early_Phase 1
- Study Result
- No
- Study Condition
- Interaction, Adverse Herb-Drug|Diabetes Mellitus, Type 2
- Study Type
- Interventional
- Study Design
- Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
- Intervention
- DRUG: Midazolam Hcl 1Mg/Ml Inj|DIETARY_SUPPLEMENT: Goldenseal (Hydrastis canadensis)
- Intervention Allocation
- Non_Randomized
- Intervention Model
- Crossover
- Intervention Mask
- Intervention Purpose
- Basic_Science
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 22
- Outcome Measure
- Metformin area under the concentration vs. time curve (AUC) ratio (exposure/baseline), Ratio of the area under the plasma concentration time curve (AUC) of metformin in the presence to absence of goldenseal., 0-24 hours
- Sponsor Collaborator
- Washington State University|National Center for Complementary and Integrative Health (NCCIH)
- Funded By
- OTHER
- Location
- Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane, Washington, 99202, United States
- Other Id
- 18889-002|U54AT008909
- Start Date
- 2021-09-16
- Primary Completion Date
- 2023-01-16
- Completion Date
- 2023-08-31
- First Posted
- 2021-10-18
- Results First Posted
- Last Update Posted
- 2023-05-10
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT05081583
- Title Cn
- Title En
- Clinical Evaluation of the Pharmacokinetic Goldenseal-Metformin Interaction in Diabetic Patients
- Bilingual Status
- semi_complete