Clinical TrialID 6840
Citrulline in Severe Sepsis
NCT01474863
Severe Sepsis|Acute Lung Injury
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 6840
- Evidence Id
- 6840
- Core Evidence Id
- 6840
- Source Clinical Trial Id
- 6831
- Herb2 Clinical Trial Id
- HBCT006831
- Nct Id
- NCT01474863
- Title
- Citrulline in Severe Sepsis
- Status
- Completed
- Phase
- Phase 2
- Study Result
- Yes
- Study Condition
- Severe Sepsis|Acute Lung Injury
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
- Intervention
- DRUG: High Dose Citrulline|DRUG: Placebo|DRUG: Low Dose Citrulline
- Intervention Allocation
- Randomized
- Intervention Model
- Single_Group
- Intervention Mask
- Triple
- Intervention Purpose
- Prevention
- Gender
- All
- Age
- Child, Adult, Older_Adult
- Enrollment
- 72
- Outcome Measure
- Vasopressor Dependency Index, Worst Value of Index measuring blood pressure hourly through study infusion (day 4). Vasopressor index is mean arterial blood pressure divided by catecholamine index (the catecholamine index is a dimensionless variable calculated as (dopamine dose × 1) + (dobutamine dose × 1) + (adrenaline dose × 10) + (noradrenaline × 100) + (phenylephrine dose × 100), where all doses are expressed in ug/kg/min). (Higher is better), day 4
- Sponsor Collaborator
- Vanderbilt University|National Institutes of Health (NIH)
- Funded By
- OTHER
- Location
- Vanderbilt University, Nashville, Tennessee, 37232, United States
- Other Id
- 111435
- Start Date
- 2012-08
- Primary Completion Date
- 2016-03
- Completion Date
- 2016-03
- First Posted
- 2011-11-18
- Results First Posted
- 2017-06-05
- Last Update Posted
- 2017-06-05
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT01474863
- Title Cn
- Title En
- Citrulline in Severe Sepsis
- Bilingual Status
- semi_complete