Clinical TrialID 6723

Randomized Study of Yohimbine Treatment for Type 2 Diabetes Patients Carrying a Specific Genetic Risk Variant

NCT01593215

Type 2 Diabetes

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Record Fields

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Clinical Trial Id
6723
Evidence Id
6723
Core Evidence Id
6723
Source Clinical Trial Id
6710
Herb2 Clinical Trial Id
HBCT006710
Nct Id
NCT01593215
Title
Randomized Study of Yohimbine Treatment for Type 2 Diabetes Patients Carrying a Specific Genetic Risk Variant
Status
Completed
Phase
Phase 2
Study Result
Yes
Study Condition
Type 2 Diabetes
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Intervention
DRUG: Yohimbine
Intervention Allocation
Randomized
Intervention Model
Crossover
Intervention Mask
Quadruple
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
50
Outcome Measure
Insulin Secretion, insulin secretion will be measured (nMole) in response to an oral glucose tolerance test. Patients will receive the capsules 1 h before the glucose test, and the insulin levels 30 minutes after the oral glucose will be used as a primary outcome measure. The insulin levels at the highest tolerated dose of yohimbine will be used., 30 minutes after oral glucose
Sponsor Collaborator
Anders Rosengren, MD PhD|Region Skane|Lund University
Funded By
OTHER
Location
Skanes Universitetssjukhus, Malmo, Skane, 20502, Sweden
Other Id
2010-018604-85
Start Date
2012-05
Primary Completion Date
2014-10
Completion Date
2014-10
First Posted
2012-05-08
Results First Posted
2015-01-09
Last Update Posted
2015-01-09
Study Document
Study Url
https://clinicaltrials.gov/study/NCT01593215
Title Cn
Title En
Randomized Study of Yohimbine Treatment for Type 2 Diabetes Patients Carrying a Specific Genetic Risk Variant
Bilingual Status
semi_complete