Clinical TrialID 6722
Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) With/Without Yohimbine
NCT01031979
Post-Traumatic Stress Disorder
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 6722
- Evidence Id
- 6722
- Core Evidence Id
- 6722
- Source Clinical Trial Id
- 6709
- Herb2 Clinical Trial Id
- HBCT006709
- Nct Id
- NCT01031979
- Title
- Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) With/Without Yohimbine
- Status
- Completed
- Phase
- Phase 2
- Study Result
- Yes
- Study Condition
- Post-Traumatic Stress Disorder
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
- Intervention
- DRUG: Yohimbine|DRUG: Placebo
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Quadruple
- Intervention Purpose
- Treatment
- Gender
- Male
- Age
- Adult
- Enrollment
- 26
- Outcome Measure
- Trauma-Cued Heart Rate Reactivity, The primary outcome was trauma-cued heart rate reactivity a week after the drug visit as measured by the PTSD Brief Reactivity (PBR) task. For each patient, a 3-minute trauma script was constructed containing vivid details of the target trauma and used in tandem with a standard neutral script for baseline measurement. Heart rate reactivity for each time point was the beats per minute (BPM) difference between the neutral and trauma scripts represented as a slope., One week after drug visit
- Sponsor Collaborator
- VA Office of Research and Development
- Funded By
- FED
- Location
- Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina, 29401-5799, United States
- Other Id
- CDA-2-013-09F
- Start Date
- 2010-12-01
- Primary Completion Date
- 2015-04-01
- Completion Date
- 2015-07-07
- First Posted
- 2009-12-15
- Results First Posted
- 2017-02-24
- Last Update Posted
- 2018-02-07
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT01031979
- Title Cn
- Title En
- Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) With/Without Yohimbine
- Bilingual Status
- semi_complete