Clinical TrialID 6612
Role of the Serotonin 5-HT2A Receptor in Mescaline-induced Altered States of Consciousness
NCT04849013
Healthy
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Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 6612
- Evidence Id
- 6612
- Core Evidence Id
- 6612
- Source Clinical Trial Id
- 6599
- Herb2 Clinical Trial Id
- HBCT006599
- Nct Id
- NCT04849013
- Title
- Role of the Serotonin 5-HT2A Receptor in Mescaline-induced Altered States of Consciousness
- Status
- Completed
- Phase
- Phase 1
- Study Result
- No
- Study Condition
- Healthy
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
- Intervention
- DRUG: Placebo|DRUG: Mescaline 100mg|DRUG: Mescaline 200mg|DRUG: Mescaline 400mg|DRUG: Mescaline 800mg|DRUG: Mescaline 800mg + Ketanserin 40mg
- Intervention Allocation
- Randomized
- Intervention Model
- Crossover
- Intervention Mask
- Quadruple
- Intervention Purpose
- Basic_Science
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 16
- Outcome Measure
- Altered States of Consciousness, 5 Dimensions of Altered States of Consciousness (5D-ASC) assesses mood, anxiety, derealization, depersonalization, changes in perception, auditory alterations, and reduced vigilance. The questionnaire is consisting of 94 items to be rated on a visual analog scale (horizontal line, 100 mm, marked with "not at all" on the left and "extremely" on the right), with higher values indicating stronger effects. Subjects will mark the scale with vertical lines., 18 months
- Sponsor Collaborator
- University Hospital, Basel, Switzerland
- Funded By
- OTHER
- Location
- University Hospital Basel, Clinical Trial Unit, Basel, BS, 4056, Switzerland
- Other Id
- BASEC 2021-00035
- Start Date
- 2021-08-11
- Primary Completion Date
- 2023-03-27
- Completion Date
- 2023-03-27
- First Posted
- 2021-04-19
- Results First Posted
- Last Update Posted
- 2023-03-29
- Study Document
- Study Url
- https://clinicaltrials.gov/study/NCT04849013
- Title Cn
- Title En
- Role of the Serotonin 5-HT2A Receptor in Mescaline-induced Altered States of Consciousness
- Bilingual Status
- semi_complete