Clinical TrialID 6605
Smell Changes & Efficacy of Nasal Theophylline
NCT03990766
Olfactory Disorder|Anosmia|Viral Infection|Theophylline Causing Adverse Effects in Therapeutic Use|Smell Disorder
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Trial: 1Ingredient: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final clinical_trial record.
- Clinical Trial Id
- 6605
- Evidence Id
- 6605
- Core Evidence Id
- 6605
- Source Clinical Trial Id
- 6592
- Herb2 Clinical Trial Id
- HBCT006592
- Nct Id
- NCT03990766
- Title
- Smell Changes & Efficacy of Nasal Theophylline
- Status
- Completed
- Phase
- Phase 2
- Study Result
- Yes
- Study Condition
- Olfactory Disorder|Anosmia|Viral Infection|Theophylline Causing Adverse Effects in Therapeutic Use|Smell Disorder
- Study Type
- Interventional
- Study Design
- Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
- Intervention
- DRUG: Theophylline|DRUG: Saline Nasal
- Intervention Allocation
- Randomized
- Intervention Model
- Parallel
- Intervention Mask
- Quadruple
- Intervention Purpose
- Treatment
- Gender
- All
- Age
- Adult, Older_Adult
- Enrollment
- 27
- Outcome Measure
- Number of Patients With Improvement in Global Rating of Smell Change, Self-reported change in smell after intervention on a 7-point Likert scale. Response options with corresponding point values: 7) Much better, 6) Somewhat better, 5) Slightly better, 4) Neither better nor worse, 3) Slightly worse, 2) Somewhat worse, and 1) Much worse. The maximum score is 7, and higher values indicate better outcomes. A score of 4 is considered neutral. Scores of 5 or higher indicated clinical improvement., 6 weeks
- Sponsor Collaborator
- Washington University School of Medicine
- Funded By
- OTHER
- Location
- Washington University in St. Louis, Saint Louis, Missouri, 63110, United States
- Other Id
- 201901107
- Start Date
- 2019-05-15
- Primary Completion Date
- 2021-01-15
- Completion Date
- 2021-01-15
- First Posted
- 2019-06-19
- Results First Posted
- 2022-03-31
- Last Update Posted
- 2022-03-31
- Study Document
- Study Protocol and Statistical Analysis Plan, https://cdn.clinicaltrials.gov/large-docs/66/NCT03990766/Prot_SAP_000.pdf|Informed Consent Form, https://cdn.clinicaltrials.gov/large-docs/66/NCT03990766/ICF_001.pdf
- Study Url
- https://clinicaltrials.gov/study/NCT03990766
- Title Cn
- Title En
- Smell Changes & Efficacy of Nasal Theophylline
- Bilingual Status
- semi_complete