Clinical TrialID 5624

Second-line Therapy for Patients With Progressive Poorly Differentiated Extra-pulmonary Neuroendocrine Carcinoma

NCT03837977

Oncology|Neuroendocrine Carcinoma

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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
5624
Evidence Id
5624
Core Evidence Id
5624
Source Clinical Trial Id
5608
Herb2 Clinical Trial Id
HBCT005608
Nct Id
NCT03837977
Title
Second-line Therapy for Patients With Progressive Poorly Differentiated Extra-pulmonary Neuroendocrine Carcinoma
Status
Active_Not_Recruiting
Phase
Phase 2
Study Result
No
Study Condition
Oncology|Neuroendocrine Carcinoma
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Intervention
DRUG: Liposomal Irinotecan|DRUG: Fluorouracil|DRUG: Folinic Acid|DRUG: Docetaxel
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Intervention Purpose
Treatment
Gender
All
Age
Adult, Older_Adult
Enrollment
102
Outcome Measure
Progression-free survival defined as a binary outcome (progression-free or not), treatment start date until 6 months, assessed at 8 weekly intervals by CT scan
Sponsor Collaborator
The Christie NHS Foundation Trust|University of Leeds|Servier|National Institute for Health Research, United Kingdom
Funded By
OTHER
Location
The Beaston West of Scotland Cancer Center, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom|Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom|The Christie NHS Foundation Trust, Manchester, M20 4BX, United Kingdom|Weston Park Hospital, Sheffield Teaching Hospitals, NHS Trust, Sheffield, United Kingdom
Other Id
CFTSp116
Start Date
2018-11-13
Primary Completion Date
2023-12-01
Completion Date
2023-12-01
First Posted
2019-02-12
Results First Posted
Last Update Posted
2023-06-09
Study Document
Study Url
https://clinicaltrials.gov/study/NCT03837977
Title Cn
Title En
Second-line Therapy for Patients With Progressive Poorly Differentiated Extra-pulmonary Neuroendocrine Carcinoma
Bilingual Status
semi_complete