Clinical TrialID 5613

Cocoa Flavanol and Coronary Vasomotion Vascular Function in Patients With Coronary Artery Disease

NCT02520466

Stable Coronary Heart Disease

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Record Fields

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Clinical Trial Id
5613
Evidence Id
5613
Core Evidence Id
5613
Source Clinical Trial Id
5596
Herb2 Clinical Trial Id
HBCT005596
Nct Id
NCT02520466
Title
Cocoa Flavanol and Coronary Vasomotion Vascular Function in Patients With Coronary Artery Disease
Status
Completed
Phase
Study Result
No
Study Condition
Stable Coronary Heart Disease
Study Type
Interventional
Study Design
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Intervention
DIETARY_SUPPLEMENT: flavanol-rich drink vs flavanol-free drink
Intervention Allocation
Randomized
Intervention Model
Parallel
Intervention Mask
Double
Intervention Purpose
Other
Gender
All
Age
Adult, Older_Adult
Enrollment
37
Outcome Measure
coronary endothelial function as assessed as response to cold pressor test, Primary endpoint will be the improvement in coronary endothelial function in response to cold pressor testing (i.e. % reduction in coronary artery constriction compared to baseline) 2h after ingestion of a cocoa flavanol rich-drink or placebo drink, respectively. In a subset of patients daily consumption of a flavanol-drink will be assessed and outcomes measured after 3-4 weeks., 2 hours
Sponsor Collaborator
University of Zurich
Funded By
OTHER
Location
Cardiovascular Center Cardiology Univeristy Hospital of Zurich, Zurich, Switzerland|Universisty Hospital of Zurich, Cardiovascular Center Cardiology, Zurich, Switzerland
Other Id
EK2012-0201
Start Date
2012-07
Primary Completion Date
2018-12-01
Completion Date
2018-12-01
First Posted
2015-08-11
Results First Posted
Last Update Posted
2019-01-11
Study Document
Study Url
https://clinicaltrials.gov/study/NCT02520466
Title Cn
Title En
Cocoa Flavanol and Coronary Vasomotion Vascular Function in Patients With Coronary Artery Disease
Bilingual Status
semi_complete