Clinical TrialID 5334

A Study to Assess the Long Term Effect, Safety and Metabolism of a Solifenacin Liquid Suspension in Participants 5 to 18 Years of Age With Neurogenic Detrusor Overactivity

NCT01565694

Neurogenic Detrusor Overactivity

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Record Fields

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Clinical Trial Id
5334
Evidence Id
5334
Core Evidence Id
5334
Source Clinical Trial Id
5320
Herb2 Clinical Trial Id
HBCT005320
Nct Id
NCT01565694
Title
A Study to Assess the Long Term Effect, Safety and Metabolism of a Solifenacin Liquid Suspension in Participants 5 to 18 Years of Age With Neurogenic Detrusor Overactivity
Status
Completed
Phase
Phase 3
Study Result
Yes
Study Condition
Neurogenic Detrusor Overactivity
Study Type
Interventional
Study Design
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Intervention
DRUG: Solifenacin succinate
Intervention Allocation
Intervention Model
Single_Group
Intervention Mask
Intervention Purpose
Treatment
Gender
All
Age
Child
Enrollment
76
Outcome Measure
Change From Baseline to Week 24 in Maximum Cystometric Capacity (MCC), During urodynamic assessments, the bladder was filled until voiding/leakage begins, or until it was stopped because either the participant experiences pain or discomfort or 135% of expected bladder capacity for age has been reached. MCC is the maximum bladder capacity reached during filling cystometry before either leakage or pain/discomfort was observed., Baseline and Week 24
Sponsor Collaborator
Astellas Pharma Europe B.V.
Funded By
INDUSTRY
Location
Site US1008, Tarrytown, New York, 10591, United States|Site US1010, Cincinnati, Ohio, 45229-3039, United States|Site BE3201, Gent, 9000, Belgium|Site BR5505, Sao Jose do Rio Preto, São Paulo, 15090-000, Brazil|Site BR5507, Campinas, 13060-803, Brazil|Site BR5504, Campinas, 13083-887, Brazil|Site BR5506, Curitiba, 80240-060, Brazil|Site BR5503, Porto Alegre, 90035-903, Brazil|Site DK4501, Aarhus, 8200, Denmark|Site HU3602, Miskolc, 3526, Hungary|Site KR8207, Seoul, 110744, Korea, Republic of|Site KR8201, Seoul, 120752, Korea, Republic of|Site MX5203, Leon, 37000, Mexico|Site MX5205, Mexico City, C.P. 06700, Mexico|Site PH6301, Manila, 1015, Philippines|Site PH6302, Quezon City, 1101, Philippines|Site PL4803, Gdansk, 80-952, Poland|Site PL4805, Gdansk, 80803, Poland|Site PL4801, Warszawa, 04-730, Poland|Site TR9003, Ankara, 6100, Turkey|Site TR9002, Izmir, 35100, Turkey
Other Id
905-CL-047|2011-000330-11
Start Date
2012-08-14
Primary Completion Date
2016-04-28
Completion Date
2016-04-28
First Posted
2012-03-29
Results First Posted
2019-05-06
Last Update Posted
2019-05-06
Study Document
Study Url
https://clinicaltrials.gov/study/NCT01565694
Title Cn
Title En
A Study to Assess the Long Term Effect, Safety and Metabolism of a Solifenacin Liquid Suspension in Participants 5 to 18 Years of Age With Neurogenic Detrusor Overactivity
Bilingual Status
semi_complete