Clinical TrialID 5280

Investigating the Gut Microbiota Modulation Effects of Allicin for Cardiovascular Disease Protection and Establishing Microbiota Directed Personalized Nutrition Guidance With Novel Humanized Gnotobiotic Mice Model, Microbial Culturomics and Metabolomic Technique

NCT04545879

Atherosclerosis

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Trial: 1Ingredient: 1Links: 1
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Record Fields

Scalar fields from the final clinical_trial record.

Clinical Trial Id
5280
Evidence Id
5280
Core Evidence Id
5280
Source Clinical Trial Id
5263
Herb2 Clinical Trial Id
HBCT005263
Nct Id
NCT04545879
Title
Investigating the Gut Microbiota Modulation Effects of Allicin for Cardiovascular Disease Protection and Establishing Microbiota Directed Personalized Nutrition Guidance With Novel Humanized Gnotobiotic Mice Model, Microbial Culturomics and Metabolomic Technique
Status
Completed
Phase
Study Result
No
Study Condition
Atherosclerosis
Study Type
Interventional
Study Design
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Intervention
DIETARY_SUPPLEMENT: Raw garlic juice containing allicin
Intervention Allocation
Intervention Model
Single_Group
Intervention Mask
Intervention Purpose
Basic_Science
Gender
All
Age
Adult, Older_Adult
Enrollment
9
Outcome Measure
Plasma and urine TMAO level (ppm), Quantitation of plasma and urine TMAO level by LC-MS, 6 months|Compositional analysis of gut microbiota (% of different bacteria species), Next-generation sequencing and bioinformatics, 6 months
Sponsor Collaborator
National Taiwan University Hospital
Funded By
OTHER
Location
National Taiwan University Hospital, Taipei, 100, Taiwan
Other Id
201712031RIND
Start Date
2019-03-18
Primary Completion Date
2019-05-18
Completion Date
2019-05-18
First Posted
2020-09-11
Results First Posted
Last Update Posted
2020-09-16
Study Document
Study Url
https://clinicaltrials.gov/study/NCT04545879
Title Cn
Title En
Investigating the Gut Microbiota Modulation Effects of Allicin for Cardiovascular Disease Protection and Establishing Microbiota Directed Personalized Nutrition Guidance With Novel Humanized Gnotobiotic Mice Model, Microbial Culturomics and Metabolomic Technique
Bilingual Status
semi_complete